X0304 4 2012-02-22 0 0000820237 GEN PROBE INC GPRO 0001542377 HANSEN BRIAN B C/O GEN-PROBE INCORPORATED 10210 GENETIC CENTER DRIVE SAN DIEGO CA 92121 0 1 0 0 SVP, Global Sales & Service Common Stock 2012-02-22 4 M 0 214 0 A 8655 D Common Stock 2012-02-22 4 F 0 71 68.18 D 8584 D Performance Stock Rights 0 2012-02-22 4 A 0 34 0 A 2012-02-22 2014-02-22 Common Stock 34 577 D Performance Stock Rights 0 2012-02-22 4 M 0 214 0 D 2014-02-22 Common Stock 214 363 D The amount reported reflects shares of the Issuer's common stock issued to the Reporting Person pursuant to performance stock rights granted to the Reporting Person in February 2011. Withholding of stock to satisfy tax withholding obligation upon vesting of shares issued to the Reporting Person as described herein. Represents additional shares subject to the performance stock rights awarded to the Reporting Person in February 2012 based on actual achievement. Remaining shares subject to the performance stock rights vest and may be issued to the Reporting Person in February 2013 and February 2014 based on the Issuer's adjusted relative stockholder return during the applicable performance periods. The amount reported reflects the remaining target number of shares of Issuer common stock that may be issued to the Reporting Person based on the Issuer's adjusted relative stockholder return for the remaining performance periods. Based on actual achievement, the Reporting Person may receive between 0% and 200% of the remaining target number of shares of Issuer common stock reported herein. /s/ R. William Bowen, Attorney-in-Fact 2012-02-24