X0202 4/A 2005-08-19 2005-08-19 0 0000820237 GEN PROBE INC GPRO 0001230048 BOWEN R WILLIAM GEN-PROBE INCORPORATED 10210 GENETIC CENTER DRIVE SAN DIEGO CA 92121 0 1 0 0 VP, General Counsel Common Stock 2005-08-19 4 S 0 200 44.71 D 9285 D Common Stock 2005-08-19 4 S 0 600 44.72 D 8685 D Common Stock 2005-08-19 4 S 0 100 44.73 D 8585 D Common Stock 2005-08-19 4 S 0 100 44.75 D 8485 D Common Stock 2005-08-19 4 S 0 100 44.76 D 8385 D Common Stock 2005-08-19 4 S 0 100 44.77 D 8285 D Common Stock 2005-08-19 4 S 0 200 44.78 D 8085 D Common Stock 2005-08-19 4 S 0 300 44.80 D 7785 D Common Stock 2005-08-19 4 S 0 1100 44.85 D 6685 D Common Stock 2005-08-19 4 S 0 100 44.86 D 6585 D Common Stock 2005-08-19 4 S 0 100 44.87 D 6485 D Common Stock 2005-08-19 4 S 0 300 44.89 D 6185 D Common Stock 2005-08-19 4 S 0 300 44.91 D 5885 D Common Stock 2005-08-19 4 S 0 300 44.92 D 5585 D Common Stock 2005-08-19 4 S 0 600 44.93 D 4985 D Common Stock 2005-08-19 4 S 0 500 44.95 D 4485 D This amendment is being filed to show the correct sale prices of the 5,000 shares previously reported on the reporting person's Form 4 previously filed on August 19, 2005. /s/ R. William Bowen 2005-08-22