Consolidated Statements of Income (Unaudited) (USD $) In Thousands, except Per Share data	3 Months Ended		6 Months Ended
	Jun. 30, 2011	Jun. 30, 2010	Jun. 30, 2011	Jun. 30, 2010
Revenues:
Product sales	$ 132,921	$ 132,734	$ 271,033	$ 263,303
Collaborative research revenue	1,617	4,141	5,185	7,405
Royalty and license revenue	1,360	1,774	2,718	3,360
Total revenues	135,898	138,649	278,936	274,068
Operating expenses:
Cost of product sales (excluding acquisition-related intangible amortization)	39,431	44,311	81,374	86,972
Acquisition-related intangible amortization	2,729	2,199	5,534	4,415
Research and development	27,713	27,104	56,676	56,785
Marketing and sales	17,510	15,824	34,032	30,605
General and administrative	18,703	15,018	36,856	29,697
Total operating expenses	106,086	104,456	214,472	208,474
Income from operations	29,812	34,193	64,464	65,594
Other income (expense):
Investment and interest income	2,937	3,269	3,672	7,167
Interest expense	(497)	(549)	(1,000)	(1,095)
Gain on contingent consideration		4,337		6,082
Other income (expense), net	1,315	(190)	1,492	(349)
Total other income, net	3,755	6,867	4,164	11,805
Income before income tax	33,567	41,060	68,628	77,399
Income tax expense	11,223	12,950	23,007	25,096
Net income	$ 22,344	$ 28,110	$ 45,621	$ 52,303
Net income per share:
Basic	$ 0.47	$ 0.57	$ 0.95	$ 1.06
Diluted	$ 0.45	$ 0.57	$ 0.93	$ 1.05
Weighted average shares outstanding:
Basic	47,884	48,902	47,873	49,066
Diluted	49,338	49,366	49,196	49,549