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        <name>Trip.com Group Ltd</name>
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        <name>NortonLifeLock Inc</name>
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        <name>MAPLEBEAR DBA INSTACART PP</name>
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        <name>salesforce.com Inc</name>
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        <name>GM CRUISE HLDG CL F CVT PFD PP</name>
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        <name>Legalzoom.com Inc</name>
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        <name>Delivery Hero SE</name>
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        <name>ALIBABA GROUP HOLDING LTD</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MESOSPHERE INC</name>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>Wix.com Ltd</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>INTUITIVE SURGICAL INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Kanzhun Ltd</name>
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          <isin value="US48553T1060"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Coupang Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Samsung Electronics Co Ltd</name>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>Deliveroo PLC</name>
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        <fairValLevel>2</fairValLevel>
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        <name>DoorDash Inc</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BOOKING HOLDINGS INC</name>
        <lei>FXM8FAOHMYDIPD38UZ17</lei>
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          <ticker value="BKNG"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>Didi Global Inc. Lockup Cusip</name>
        <lei>N/A</lei>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>MICROSOFT CORP</name>
        <lei>INR2EJN1ERAN0W5ZP974</lei>
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        <fairValLevel>1</fairValLevel>
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        <name>Zalando SE</name>
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        <title>Zalando SE</title>
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        <name>Slack Technologies Inc</name>
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        <name>Wayfair Inc</name>
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        <name>Workday Inc</name>
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        <title>Workday Inc</title>
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        <name>MICRON TECHNOLOGY INC</name>
        <lei>B3DXGBC8GAIYWI2Z0172</lei>
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          <ticker value="MU"/>
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        <name>VeriSign Inc</name>
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        <name>MAPLEBEAR DBA INSTACART NON-VOTING PP</name>
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        <title>MAPLEBEAR DBA INSTACART NON-VOTING PP</title>
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        <name>Baidu Inc</name>
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        <title>Baidu Inc</title>
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        <invCountry>CN</invCountry>
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        <name>WAYMO LLC SER B-2 CVT PFD UNITS PP</name>
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        <title>WAYMO LLC SER B-2 CVT PFD UNITS PP</title>
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        <name>CTS Eventim AG &amp; Co KGaA</name>
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        <title>CTS Eventim AG &amp; Co KGaA</title>
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          <ticker value="EVD"/>
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        <invCountry>DE</invCountry>
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        <fairValLevel>2</fairValLevel>
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        <name>COUPANG INC</name>
        <lei>N/A</lei>
        <title>COUPANG INC</title>
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        <invCountry>US</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>EPIC GAMES INC PP</name>
        <lei>N/A</lei>
        <title>EPIC GAMES INC PP</title>
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        </identifiers>
        <balance>55791.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>49375035.00000000</valUSD>
        <pctVal>0.476597297318</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Mail.Ru Group Ltd</name>
        <lei>2138009IXUP41SPL5B50</lei>
        <title>Mail.Ru Group Ltd</title>
        <cusip>560317208</cusip>
        <identifiers>
          <isin value="US5603172082"/>
          <ticker value="MAIL"/>
          <other otherDesc="SEDOL" value="B53NQB3"/>
        </identifiers>
        <balance>11080422.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>251888663.31000000</valUSD>
        <pctVal>2.431379667046</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>RU</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Naspers Ltd</name>
        <lei>21380044BQ8812EEKT59</lei>
        <title>Naspers Ltd</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="ZAE000015889"/>
          <ticker value="NPN"/>
          <other otherDesc="SEDOL" value="6622691"/>
        </identifiers>
        <balance>679710.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="ZAR" exchangeRt="14.28000000"/>
        <valUSD>143314812.94000000</valUSD>
        <pctVal>1.383360082942</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>ZA</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>QUALCOMM Inc</name>
        <lei>H1J8DDZKZP6H7RWC0H53</lei>
        <title>QUALCOMM Inc</title>
        <cusip>747525103</cusip>
        <identifiers>
          <isin value="US7475251036"/>
          <ticker value="QCOM"/>
        </identifiers>
        <balance>1173517.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>167730784.81000000</valUSD>
        <pctVal>1.619037611163</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Xilinx Inc</name>
        <lei>6EY4K7ZMF9UX1CU6KC79</lei>
        <title>Xilinx Inc</title>
        <cusip>983919101</cusip>
        <identifiers>
          <isin value="US9839191015"/>
          <ticker value="XLNX"/>
        </identifiers>
        <balance>1870000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>270476800.00000000</valUSD>
        <pctVal>2.610803452945</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TeamViewer AG</name>
        <lei>3912000FZ0R0KEK9JS42</lei>
        <title>TeamViewer AG</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="DE000A2YN900"/>
          <ticker value="TMV"/>
          <other otherDesc="SEDOL" value="BJ7WGS1"/>
        </identifiers>
        <balance>2670316.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.84334809"/>
        <valUSD>100288950.93000000</valUSD>
        <pctVal>0.968048791542</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>McAfee Corp</name>
        <lei>N/A</lei>
        <title>McAfee Corp</title>
        <cusip>579063108</cusip>
        <identifiers>
          <isin value="US5790631080"/>
          <ticker value="MCFE"/>
        </identifiers>
        <balance>3169187.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>88800619.74000000</valUSD>
        <pctVal>0.857156564411</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JAND INC</name>
        <lei>N/A</lei>
        <title>JAND INC (DBA WARBY PARKER) CL A PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="INTERNAL" value="TC5QAMIM5"/>
        </identifiers>
        <balance>656699.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>16109220.49000000</valUSD>
        <pctVal>0.155495807697</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Applied Materials Inc</name>
        <lei>41BNNE1AFPNAZELZ6K07</lei>
        <title>Applied Materials Inc</title>
        <cusip>038222105</cusip>
        <identifiers>
          <isin value="US0382221051"/>
          <ticker value="AMAT"/>
        </identifiers>
        <balance>1064185.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>151539944.00000000</valUSD>
        <pctVal>1.462753955438</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FACEBOOK INC</name>
        <lei>BQ4BKCS1HXDV9HN80Z93</lei>
        <title>FACEBOOK INC-A</title>
        <cusip>30303M102</cusip>
        <identifiers>
          <isin value="US30303M1027"/>
          <ticker value="FB"/>
        </identifiers>
        <balance>1169529.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>406656928.59000000</valUSD>
        <pctVal>3.925295305649</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Zoom Video Communications Inc</name>
        <lei>549300T9GCHU0ODOM055</lei>
        <title>Zoom Video Communications Inc</title>
        <cusip>98980L101</cusip>
        <identifiers>
          <isin value="US98980L1017"/>
          <ticker value="ZM"/>
        </identifiers>
        <balance>982138.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>380116870.14000000</valUSD>
        <pctVal>3.669114826426</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>boohoo Group PLC</name>
        <lei>213800SZF3KFCECWY243</lei>
        <title>boohoo Group PLC</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="JE00BG6L7297"/>
          <ticker value="BOO"/>
          <other otherDesc="SEDOL" value="BG6L729"/>
        </identifiers>
        <balance>26102816.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="GBP" exchangeRt="0.72290898"/>
        <valUSD>112071823.86000000</valUSD>
        <pctVal>1.081784111286</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AMAZON.COM INC</name>
        <lei>ZXTILKJKG63JELOEG630</lei>
        <title>AMAZON.COM INC</title>
        <cusip>023135106</cusip>
        <identifiers>
          <isin value="US0231351067"/>
          <ticker value="AMZN"/>
        </identifiers>
        <balance>167414.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>575930946.24000000</valUSD>
        <pctVal>5.559229120951</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Monday.com Ltd</name>
        <lei>N/A</lei>
        <title>Monday.com Ltd</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="IL0011762130"/>
          <ticker value="MNDY"/>
          <other otherDesc="SEDOL" value="BMHRYX8"/>
        </identifiers>
        <balance>35106.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7849350.54000000</valUSD>
        <pctVal>0.075766614708</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Array Technologies Inc</name>
        <lei>N/A</lei>
        <title>Array Technologies Inc</title>
        <cusip>04271T100</cusip>
        <identifiers>
          <isin value="US04271T1007"/>
          <ticker value="ARRY"/>
        </identifiers>
        <balance>777886.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>12135021.60000000</valUSD>
        <pctVal>0.117134468815</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Visa Inc</name>
        <lei>549300JZ4OKEHW3DPJ59</lei>
        <title>Visa Inc</title>
        <cusip>92826C839</cusip>
        <identifiers>
          <isin value="US92826C8394"/>
          <ticker value="V"/>
        </identifiers>
        <balance>640700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>149808474.00000000</valUSD>
        <pctVal>1.446040773921</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2021-08-23</ncom:dateSigned>
      <ncom:nameOfApplicant>T. ROWE PRICE SCIENCE &amp; TECHNOLOGY FUND, INC.</ncom:nameOfApplicant>
      <ncom:signature>Alan S. Dupski</ncom:signature>
      <ncom:signerName>Alan S. Dupski</ncom:signerName>
      <ncom:title>Treasurer &amp; Vice President</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
