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        <name>SYNOPSYS INC</name>
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      <invstOrSec>
        <name>NortonLifeLock Inc.</name>
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        <name>ALIBABA GROUP HOLDING LTD</name>
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        <name>T ROWE PRICE TREASURY RESERVE FUND</name>
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        <fairValLevel>1</fairValLevel>
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        <name>MESOSPHERE INC</name>
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        <name>XIAOJU KUAIZHI INC</name>
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        <name>Naspers Ltd</name>
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        <name>NEWS CORP</name>
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        <name>NVIDIA Corp</name>
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        <name>Workday Inc</name>
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        <name>BOOKING HOLDINGS INC</name>
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        <name>Zalando SE</name>
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        <invCountry>DE</invCountry>
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        <name>GM CRUISE HLDG CL F CVT PFD PP</name>
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        <name>GSX Techedu Inc</name>
        <lei>549300R5BPFFORR9ET36</lei>
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        <name>Prosus NV</name>
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        <name>Netflix Inc</name>
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        <title>Netflix Inc</title>
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        <name>AMAZON.COM INC</name>
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        <name>COUPANG LLC</name>
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        <name>Mail.Ru Group Ltd</name>
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        <name>Pure Storage Inc</name>
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        <name>INTUITIVE SURGICAL INC</name>
        <lei>54930052SRG011710797</lei>
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        <name>NAVER Corp</name>
        <lei>N/A</lei>
        <title>NAVER Corp</title>
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      <invstOrSec>
        <name>58.com Inc</name>
        <lei>549300R31W8UMZCTNF95</lei>
        <title>58.com Inc</title>
        <cusip>31680Q104</cusip>
        <identifiers>
          <isin value="US31680Q1040"/>
          <ticker value="WUBA"/>
        </identifiers>
        <balance>3405755.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>220454521.15000000</valUSD>
        <pctVal>3.215376907388</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CN</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Electronic Arts Inc</name>
        <lei>549300O7A67PUEYKDL45</lei>
        <title>Electronic Arts Inc</title>
        <cusip>285512109</cusip>
        <identifiers>
          <isin value="US2855121099"/>
          <ticker value="EA"/>
        </identifiers>
        <balance>451400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>48530014.00000000</valUSD>
        <pctVal>0.707820758299</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JAND INC (DBA WARBY PARKER) CVT SER E PP</name>
        <lei>N/A</lei>
        <title>JAND INC (DBA WARBY PARKER) CVT SER E PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal" value="933TAC903"/>
        </identifiers>
        <balance>810105.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>14713127.01000000</valUSD>
        <pctVal>0.214594142032</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Applied Materials Inc</name>
        <lei>41BNNE1AFPNAZELZ6K07</lei>
        <title>Applied Materials Inc</title>
        <cusip>038222105</cusip>
        <identifiers>
          <isin value="US0382221051"/>
          <ticker value="AMAT"/>
        </identifiers>
        <balance>1299100.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>79297064.00000000</valUSD>
        <pctVal>1.156564841942</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>salesforce.com Inc</name>
        <lei>RCGZFPDMRW58VJ54VR07</lei>
        <title>salesforce.com Inc</title>
        <cusip>79466L302</cusip>
        <identifiers>
          <isin value="US79466L3024"/>
          <ticker value="CRM"/>
        </identifiers>
        <balance>2295656.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>373365491.84000000</valUSD>
        <pctVal>5.445616511812</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FACEBOOK INC</name>
        <lei>BQ4BKCS1HXDV9HN80Z93</lei>
        <title>FACEBOOK INC-A</title>
        <cusip>30303M102</cusip>
        <identifiers>
          <isin value="US30303M1027"/>
          <ticker value="FB"/>
        </identifiers>
        <balance>2885529.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>592254827.25000000</valUSD>
        <pctVal>8.638164846405</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JAND INC</name>
        <lei>N/A</lei>
        <title>JAND INC (DBA WARBY PARKER) CL A PP</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="INTERNAL" value="TC5QAMIM5"/>
        </identifiers>
        <balance>656699.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11926967.24000000</valUSD>
        <pctVal>0.173957398735</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>T. ROWE PRICE SHORT-TERM FUND</name>
        <lei>549300YTML4H25P65J89</lei>
        <title>T. ROWE PRICE SHORT-TERM FUND</title>
        <cusip>000000000</cusip>
        <identifiers>
          <ticker value="REI"/>
          <other otherDesc="Internal" value="76105Y976"/>
        </identifiers>
        <balance>599604.50000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5996045.00000000</valUSD>
        <pctVal>0.087453614142</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="5996045" isCashCollateral="Y"/>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MICRON TECHNOLOGY INC</name>
        <lei>B3DXGBC8GAIYWI2Z0172</lei>
        <title>MICRON TECHNOLOGY INC</title>
        <cusip>595112103</cusip>
        <identifiers>
          <isin value="US5951121038"/>
          <ticker value="MU"/>
        </identifiers>
        <balance>2419399.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>130115278.22000000</valUSD>
        <pctVal>1.897759495720</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Samsung Electronics Co Ltd</name>
        <lei>9884007ER46L6N7EI764</lei>
        <title>Samsung Electronics Co Ltd</title>
        <cusip>000000000</cusip>
        <identifiers>
          <isin value="KR7005930003"/>
          <ticker value="005930"/>
          <other otherDesc="SEDOL" value="6771720"/>
        </identifiers>
        <balance>7460291.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="KRW" exchangeRt="1156.45000000"/>
        <valUSD>359488229.91000000</valUSD>
        <pctVal>5.243213642890</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>INTUIT INC</name>
        <lei>VI90HBPH7XSFMB9E4M29</lei>
        <title>INTUIT INC</title>
        <cusip>461202103</cusip>
        <identifiers>
          <isin value="US4612021034"/>
          <ticker value="INTU"/>
        </identifiers>
        <balance>162187.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>42481640.91000000</valUSD>
        <pctVal>0.619603927637</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2020-02-24</ncom:dateSigned>
      <ncom:nameOfApplicant>T. ROWE PRICE SCIENCE &amp; TECHNOLOGY FUND, INC.</ncom:nameOfApplicant>
      <ncom:signature>Alan S. Dupski</ncom:signature>
      <ncom:signerName>Alan S. Dupski</ncom:signerName>
      <ncom:title>Treasurer &amp; Vice President</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
