X0306 4 2020-09-15 0000819050 Brickell Biotech, Inc. BBI 0001123343 LYONS GARY A C/O BRICKELL BIOTECH, INC. 5777 CENTRAL AVENUE, SUITE 102 BOULDER CO 80301 1 0 0 0 Common Stock 2020-09-15 4 A 0 11934 0.81 A 24729 D Stock Option (right to buy) .80 2020-09-15 4 A 0 60000 0 A 2030-09-15 Common Stock 60000 60000 D On September 15, 2020, the reporting person was granted 11,934 restricted stock units ("RSUs") in lieu of a portion of cash compensation as a director of Brickell Biotech, Inc. The RSUs are scheduled to vest on December 31, 2020 and will be settled in the form of one share of common stock for each RSU. The stock options will vest 25% on September 15, 2021, and the remainder will vest in equal monthly installments over the following three years. /s/ Christine G. Long, Attorney-in-Fact for Gary A. Lyons (power of attorney previously filed) 2020-09-17