X0306 4 2020-08-31 0000819050 Brickell Biotech, Inc. BBI 0001008105 HARDY REGINALD L C/O BRICKELL BIOTECH, INC. 5777 CENTRAL AVENUE, SUITE 102 BOULDER CO 80301 1 1 0 0 Chairman of the Board Common Stock 2020-08-31 4 M 0 883 A 197954 D Common Stock 2020-08-31 4 F 0 283 .94 D 197671 D Common Stock 2020-08-31 4 F 0 7048 .94 D 190623 D Common Stock 9261 I By Spouse Common Stock 21826 I By Spouse (spouse jointly owns with other Individual) Common Stock 17260 I By Spouse as Trustee Common Stock 266447 I By Self as General Partner Common Stock 17260 I By Self as Trustee Restricted Stock Units 2020-08-31 4 M 0 883 0 D Common Stock 883 0 D Restricted stock units ("RSUs") converted into common stock on a one-for-one basis. Represents shares withheld to satisfy tax withholding obligations upon the vesting of RSUs. These RSUs were granted on February 14, 2020 and vest in installments through August 31, 2020. /s/ Christine G. Long, Attorney-in-Fact for Reginald L. Hardy (power of attorney previously filed) 2020-09-02