Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenues:
Net product sales	$ 26,557	$ 23,230	$ 77,644	$ 65,691
Operating expenses:
Cost of product sales	14,717	11,351	42,247	35,080
Research and development	25,545	28,595	96,449	101,944
General and administrative	9,799	9,786	28,513	30,266
Sales and marketing	18,378	25,206	64,738	62,692
Total operating expenses	68,439	74,938	231,947	229,982
Loss from operations	(41,882)	(51,708)	(154,303)	(164,291)
Other expense, net	(26)	(700)	(7,852)	(1,746)
Net loss	(41,908)	(52,408)	(162,155)	(166,037)
Other comprehensive loss:
Unrealized losses on short-term investments	(46)	(45)	(51)	(261)
Comprehensive loss	$ (41,954)	$ (52,453)	$ (162,206)	$ (166,298)
Basic net loss per share	$ (0.38)	$ (0.51)	$ (1.54)	$ (1.71)
Shares used in computing basic net loss per share	111,735	101,906	105,456	97,290
Diluted net loss per share	$ (0.38)	$ (0.51)	$ (1.54)	$ (1.71)
Shares used in computing diluted net loss per share	111,735	101,906	105,456	97,290