Inventory - Additional Information (Details) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Inventory [Line Items]
Total inventory	$ 56,470	$ 48,382
ZYNRELEF
Inventory [Line Items]
Total inventory	34,300	23,600
SUSTOL
Inventory [Line Items]
Total inventory	1,300	1,700
CINVANTI
Inventory [Line Items]
Total inventory	$ 20,900	$ 23,100