Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Revenues:
Net product sales	$ 23,457	$ 20,018
Operating expenses:
Cost of product sales	11,355	9,207
Research and development	42,070	38,116
General and administrative	9,533	9,573
Sales and marketing	23,422	15,236
Total operating expenses	86,380	72,132
Loss from operations	(62,923)	(52,114)
Other expense, net	(965)	(500)
Net loss	(63,888)	(52,614)
Other comprehensive loss:
Unrealized losses on short-term investments	(2)	(136)
Comprehensive loss	$ (63,890)	$ (52,750)
Basic and diluted net loss per share	$ (0.63)	$ (0.58)
Shares used in computing basic and diluted net loss per share	102,123	91,388