Accounting Policies - Additional Information (Details) - USD ($)	3 Months Ended
	Mar. 31, 2022	Mar. 31, 2021
Product Information [Line Items]
Net product sales	$ 23,457,000	$ 20,018,000
Accounting Standards Update 2020-06
Product Information [Line Items]
Change in accounting principle, accounting standards update, adopted	true
Change in accounting principle, accounting standards update, immaterial effect	true
CINVANTI
Product Information [Line Items]
Net product sales	$ 20,300,000	18,500,000
SUSTOL
Product Information [Line Items]
Net product sales	2,100,000	1,500,000
ZYNRELEF
Product Information [Line Items]
Net product sales	$ 1,100,000	$ 0