Condensed Consolidated Balance Sheets (Current Period Unaudited) - USD ($) $ in Thousands	Mar. 31, 2022	Dec. 31, 2021
Current assets:
Cash and cash equivalents	$ 56,911	$ 90,541
Short-term investments	54,999	67,039
Accounts receivable, net	41,103	35,499
Inventory	56,470	48,382
Prepaid expenses and other current assets	13,110	12,962
Total current assets	222,593	254,423
Property and equipment, net	23,858	23,734
Right-of-use lease assets	9,295	9,829
Other assets	17,977	17,720
Total assets	273,723	305,706
Current liabilities:
Accounts payable	8,226	3,803
Accrued clinical and manufacturing liabilities	37,277	23,716
Accrued payroll and employee liabilities	12,214	15,263
Other accrued liabilities	32,800	25,859
Current lease liabilities	2,484	2,417
Total current liabilities	93,001	71,058
Non-current lease liabilities	7,391	7,996
Non-current convertible notes payable, net	149,132	149,082
Other non-current liabilities	241
Total liabilities	249,765	228,136
Stockholders’ equity:
Common stock	1,021	1,020
Additional paid-in capital	1,700,264	1,689,987
Accumulated other comprehensive loss	(8)	(6)
Accumulated deficit	(1,677,319)	(1,613,431)
Total stockholders’ equity	23,958	77,570
Total liabilities and stockholders’ equity	$ 273,723	$ 305,706