Balance Sheet Details - Additional Information (Details) - USD ($)	12 Months Ended
Dec. 31, 2021	Dec. 31, 2020	Dec. 31, 2019
Debt securities, impairment losses	$ 0	$ 0
Debt securities, available-for-sale, unrealized gain (loss)	(300,000)	200,000	$ 200,000
Debt securities, available-for-sale, realized gain (loss)	0	0	8,000
Inventory	48,382,000	41,905,000
Depreciation and amortization	3,021,000	2,847,000	$ 2,044,000
Construction in Progress, Gross	15,900,000	14,100,000
ZYNRELEF
Inventory	23,600,000
SUSTOL
Inventory	1,700,000	4,100,000
Cost of product sales, charges	3,800,000	100,000
CINVANTI
Inventory	$ 23,100,000	$ 37,800,000

Amount of structure or a modification to a structure under construction. Includes recently completed structures or modifications to structures that have not been placed into service.

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Amount of realized gain (loss) on investment in debt security measured at fair value with change in fair value recognized in other comprehensive income (available-for-sale).

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The aggregate expense recognized in the current period that allocates the cost of tangible assets, intangible assets, or depleting assets to periods that benefit from use of the assets.

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Nonrecurring impairment charges related to the write-off of production-related equipment and inventory. This tag is used when an Entity charges this cost to cost of goods sold.

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