Inventory - Additional Information (Details) - USD ($) $ in Thousands	3 Months Ended	9 Months Ended
	Sep. 30, 2021	Sep. 30, 2021	Dec. 31, 2020
Inventory [Line Items]
Total inventory	$ 41,502	$ 41,502	$ 41,905
CINVANTI
Inventory [Line Items]
Total inventory	25,500	25,500	37,800
SUSTOL
Inventory [Line Items]
Total inventory	2,300	2,300	$ 4,100
Cost of product sales, charges	400	3,500
ZYNRELEF
Inventory [Line Items]
Total inventory	$ 13,700	$ 13,700