Condensed Consolidated Statements of Operations and Comprehensive Loss (Unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended
	Mar. 31, 2020	Mar. 31, 2019
Revenues:
Net product sales	$ 25,400	$ 31,602
Operating expenses:
Cost of product sales	10,622	14,962
Research and development	36,894	42,972
General and administrative	10,422	9,648
Sales and marketing	20,196	28,720
Total operating expenses	78,134	96,302
Loss from operations	(52,734)	(64,700)
Other income, net	1,155	1,688
Net loss	(51,579)	(63,012)
Other comprehensive income:
Unrealized gains on short-term investments	623	123
Comprehensive loss	$ (50,956)	$ (62,889)
Basic and diluted net loss per share	$ (0.57)	$ (0.80)
Shares used in computing basic and diluted net loss per share	90,409	78,419