Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 71,898	$ 31,836
Short-term investments	319,074	300,535
Accounts receivable, net	39,879	64,652
Inventory	24,968	39,032
Prepaid expenses and other current assets	23,245	11,193
Total current assets	479,064	447,248
Property and equipment, net	19,618	14,677
Right-of-use lease assets	13,754
Other assets	346	254
Total assets	512,782	462,179
Current liabilities:
Accounts payable	2,758	16,863
Accrued clinical and manufacturing liabilities	34,614	24,470
Accrued payroll and employee liabilities	15,248	13,397
Other accrued liabilities	36,535	32,715
Current lease liabilities	1,926
Convertible notes payable to related parties, net of discount	5,624	4,574
Total current liabilities	96,705	92,019
Non-current lease liabilities	12,242
Total liabilities	108,947	92,019
Commitments and contingencies (see Note 6)
Stockholders’ equity:
Preferred stock, $0.01 par value: 2,500 shares authorized; no shares issued or outstanding at December 31, 2019 and 2018
Common stock, $0.01 par value: 150,000 shares authorized; 90,304 and 78,174 shares issued and outstanding at December 31, 2019 and 2018, respectively	903	782
Additional paid-in capital	1,568,317	1,330,186
Accumulated other comprehensive income (loss)	85	(87)
Accumulated deficit	(1,165,470)	(960,721)
Total stockholders’ equity	403,835	370,160
Total liabilities and stockholders’ equity	$ 512,782	$ 462,179