Condensed Consolidated Balance Sheets (Current Period Unaudited) - USD ($) $ in Thousands	Jun. 30, 2019	Dec. 31, 2018
Current assets:
Cash and cash equivalents	$ 53,038	$ 31,836
Short-term investments	222,967	300,535
Accounts receivable, net	66,821	64,652
Inventory	29,270	39,032
Prepaid expenses and other current assets	8,739	11,193
Total current assets	380,835	447,248
Property and equipment, net	17,910	14,677
Right-of-use lease assets	12,667
Other assets	254	254
Total assets	411,666	462,179
Current liabilities:
Accounts payable	7,997	16,863
Accrued clinical and manufacturing liabilities	25,383	24,470
Accrued payroll and employee liabilities	8,982	13,397
Other accrued liabilities	45,891	32,715
Current lease liabilities	1,722
Convertible notes payable to related parties, net of discount	5,081	4,574
Total current liabilities	95,056	92,019
Non-current lease liabilities	11,251
Total liabilities	106,307	92,019
Stockholders’ equity:
Common stock	798	782
Additional paid-in capital	1,378,368	1,330,186
Accumulated other comprehensive income (loss)	148	(87)
Accumulated deficit	(1,073,955)	(960,721)
Total stockholders’ equity	305,359	370,160
Total liabilities and stockholders’ equity	$ 411,666	$ 462,179