X0508 4 2024-01-19 0 0000818033 HERON THERAPEUTICS, INC. /DE/ HRTX 0001964335 Morgan Adam 4242 CAMPUS POINT COURT, SUITE 200 SAN DIEGO CA 92121 1 0 0 0 0 Common Stock 2024-01-19 4 A 0 13948 0.00 A 51827 D Common Stock 6986744 I By Velan Capital Master Fund LP Stock Option (Right to Buy) 2.09 2024-01-19 4 A 0 83685 0.00 A 2034-01-19 Common Stock 83685 83685 D The shares were granted as restricted stock units which vest in full on January 19, 2025. Securities owned directly by Velan Master. Mr. Morgan, as a managing member of each of Velan Capital Holdings LLC, the general partner of Velan Master, and Velan Capital Management LLC, the general partner of the investment manager of Velan Master, may be deemed to beneficially own the securities owned directly by Velan Master. Mr. Morgan disclaims beneficial ownership of the securities reported herein except to the extent of his pecuniary interest therein, and this report shall not be deemed to be an admission that Mr. Morgan is the beneficial owner of such securities for purposes of Section 16 or for any other purpose. The stock options vest and become exercisable in 12 equal monthly installments beginning one month after the date of grant. /s/ Lisa Peraza Attorney-in-fact for Adam Morgan 2024-01-19