Consolidated Statements of Cash Flows - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Operating activities:
Net loss	$ (13,580)	$ (110,559)	$ (182,024)
Adjustments to reconcile net loss to net cash used for operating activities:
Stock-based compensation expense	12,962	32,854	42,980
Depreciation and amortization	2,492	2,899	2,889
Amortization of debt discount	751	133
Amortization of debt issuance costs	210	206	202
Accretion of discount on short-term investments	(2,143)	(1,739)	(736)
Retirement and impairment of property and equipment	4,409	617	209
(Gain)/Loss on disposal of property and equipment	(27)	10	74
Change in operating assets and liabilities:
Accounts receivable	(18,744)	(8,088)	(16,550)
Inventory	(11,050)	12,463	(6,191)
Prepaid expenses and other assets	(9,927)	15,426	1,010
Accounts payable	8,469	15	(578)
Accrued clinical and manufacturing liabilities	3,220	(2,177)	752
Accrued payroll and employee liabilities	330	(4,192)	(1,847)
Other accrued liabilities	99	3,343	12,898
Net cash used in operating activities	(22,529)	(58,789)	(146,912)
Investing activities:
Purchases of short-term investments	(103,087)	(87,658)	(145,683)
Maturities and sales of short-term investments	123,480	107,185	143,957
Purchases of property and equipment	(1,706)	(1,545)	(1,825)
Proceeds from the sale of property and equipment	27	13	227
Net cash provided by (used in) investing activities	18,714	17,995	(3,324)
Financing activities:
Net proceeds from sale of common stock		29,755	75,145
Net proceeds from notes financing		24,350
Proceeds from purchases under the Employee Stock Purchase Plan	637	904	1,444
Receipts (payments) for stock issued under the equity incentive plan	303	(903)	(1,530)
Proceeds from warrant exercises		1
Net cash provided by financing activities	940	54,107	75,059
Net (decrease) increase in cash and cash equivalents	(2,875)	13,313	(75,177)
Cash and cash equivalents at beginning of year	28,677	15,364	90,541
Cash and cash equivalents at end of year	25,802	28,677	15,364
Supplemental disclosure of cash flow information:
Interest paid	$ 4,860	$ 3,059	$ 2,250