Organization and Business - Additional Information (Details) - USD ($) $ in Thousands	12 Months Ended
	Dec. 31, 2023	Dec. 31, 2022
Business [Line Items]
Accumulated deficit	$ (1,906,014)	$ (1,795,455)
Cash, cash equivalents and short-term investments	80,400
Net loss	$ (110,559)	$ (182,024)