COVER 2 filename2.txt J. & W. Seligman & Co. Incorporated February 28, 2006 Securities and Exchange Commission 100 F Street, NE Washington, DC 20549 Re: Seligman Portfolios, Inc. (the "Fund") Post-Effective Amendment No. 35 File Nos. 33-15253 and 811-5221 Dear Sir or Madam: Filed herewith is a Post-Effective Amendment No. 35 to the Registration Statement on Form N-1A of the Fund filed pursuant to Rule 485(a)(1) under the Securities Act of 1933, as amended, and Amendment No. 37 under the Investment Company Act of 1940, as amended. This filing has been marked to show changes from Post-Effective Amendment No. 34 filed on April 29, 2005. This Post-Effective Amendment No. 35 is being filed to reflect a change in the way securities are chosen for investment in the Fund's Seligman Common Stock Portfolio, as described in the section "Principal Investment Strategies" on page 8 of the Fund's Prospectus, among other non-material changes to the Fund's Prospectus. If you have any questions or comments, please contact the undersigned at (212) 850-1703. Very truly yours, /s/ Joseph L. D'Alessandro ----------------------------- Joseph L. D'Alessandro Vice President Law & Regulation JLD/jgm 100 Park Avenue New York, NY 10017 (212) 850-1864