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Share-Based Compensation (Components of Share-Based Compensation Expense) (Details) - USD ($)
$ in Millions
3 Months Ended 6 Months Ended
Jun. 30, 2016
Jun. 30, 2015
Jun. 30, 2016
Jun. 30, 2015
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total share-based compensation expense $ 157.5 $ 147.7 $ 304.0 $ 276.5
Tax benefit related to share-based compensation expense 44.0 44.8 84.1 81.2
Reduction in income 113.5 102.9 219.9 195.3
Cost of goods sold (excluding amortization of acquired intangible assets)        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total share-based compensation expense 8.7 8.1 17.7 14.8
Research and development        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total share-based compensation expense 63.9 63.6 126.1 119.8
Selling, general and administrative        
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]        
Total share-based compensation expense $ 84.9 $ 76.0 $ 160.2 $ 141.9