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CONSOLIDATED STATEMENTS OF CASH FLOWS - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2016
Mar. 31, 2015
Cash flows from operating activities:    
Net income $ 800.7 $ 718.9
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation 29.2 28.1
Amortization 96.1 66.6
Deferred income taxes (43.4) (106.6)
Impairment charges 17.4 2.1
Change in value of contingent consideration 33.0 19.0
Gain on sale of business (37.5) 0.0
Share-based compensation expense 146.5 128.8
Share-based employee benefit plan expense 9.0 7.7
Derivative instruments 21.3 (7.0)
Other, net (2.3) 0.6
Change in current assets and liabilities, excluding the effect of acquisitions:    
Accounts receivable 23.1 (59.5)
Inventory (25.6) 7.3
Other operating assets 38.6 (26.4)
Accounts payable and other operating liabilities (130.3) 59.2
Income tax payable (2.8) 15.8
Deferred revenue 1.9 1.9
Net cash provided by operating activities 974.9 856.5
Cash flows from investing activities:    
Proceeds from sales of marketable securities available for sale 313.9 1,079.8
Purchases of marketable securities available for sale (285.4) (678.8)
Capital expenditures (59.6) (42.3)
Proceeds from sales of investment securities 0.3 6.8
Purchases of investment securities (79.4) (27.5)
Net cash (used in) provided by investing activities (110.2) 338.0
Cash flows from financing activities:    
Payment for treasury shares (1,410.0) (1,012.6)
Proceeds from short-term borrowing 0.0 90.0
Principal repayments on short-term borrowing 0.0 (189.6)
Net proceeds from common equity put options 2.8 5.2
Net proceeds from share-based compensation arrangements 62.4 114.4
Excess tax benefit from share-based compensation arrangements 25.1 84.5
Net cash used in financing activities (1,319.7) (908.1)
Effect of currency rate changes on cash and cash equivalents 20.2 (40.3)
Net (decrease) increase in cash and cash equivalents (434.8) 246.1
Cash and cash equivalents at beginning of period 4,880.3 4,121.6
Cash and cash equivalents at end of period 4,445.5 4,367.7
Supplemental schedule of non-cash investing and financing activity:    
Change in net unrealized loss on marketable securities available for sale 381.8 77.1
Investment in Human Longevity, Inc. common stock 39.6 0.0
Supplemental disclosure of cash flow information:    
Interest paid 200.9 50.2
Income taxes paid $ 102.1 $ 106.7