Collaboration Agreements (Tables)

3 Months Ended

Mar. 31, 2016

Collaboration Agreements [Abstract]

Schedule of Collaboration Agreements

A financial summary of certain period activity related to our collaboration agreements is presented below^1,2:

		Three-Month Periods Ended March 31,
		Research and Development Expense
		Upfront Fees	Milestones	Extension/Termination of Agreements	Amortization of Prepaid Research and Development	Equity Investments Made During Period
bluebird	2016	$10.0	$—	$—	$2.1	$—
	2015	—	—	—	—	—
Juno3	2016	—	—	—	—	41.0
	2015	—	—	—	—	—
Other Collaboration Arrangements	2016	70.0	65.0	—	3.9	37.0
	2015	19.0	—	8.1	5.5	—

A financial summary of the period-end balances related to our collaboration agreements is presented below:

	Balances as of:	Intangible Asset Balance	Equity Investment Balance	Percentage of Outstanding Equity
Acceleron	March 31, 2016	$—	$142.8	15%
	December 31, 2015	—	224.9	14%
bluebird	March 31, 2016	18.1	N/A	N/A
	December 31, 2015	20.2	N/A	N/A
Juno	March 31, 2016	—	391.4	10%
	December 31, 2015	—	401.8	9%
Other Collaboration Arrangements	March 31, 2016	48.5	487.4	N/A
	December 31, 2015	52.4	702.4	N/A

¹  Activity and balances are presented specifically for notable new collaborations and for those collaborations which we have described in detail in our 2015 Annual Report on Form 10-K if there has been new significant activity during the periods presented. Amounts related to collaborations that are not specifically presented are included in the aggregate as Other Collaboration Arrangements.

²  In addition to the expenses noted in the tables above, we may also incur expenses for collaboration agreement related activities that are managed or funded by us.

³  Our equity investment in Juno made in the first quarter of 2016 was transacted at a price per share that exceeded the market value of Juno's publicly traded common stock on the transaction closing date, resulting in an expense for the premium of $6.0 million that was recorded in the Consolidated Statements of Income as Other income (expense), net in the first quarter of 2016.