CONSOLIDATED STATEMENTS OF INCOME - USD ($) shares in Millions, $ in Millions	3 Months Ended
	Mar. 31, 2016	Mar. 31, 2015
Revenue:
Net product sales	$ 2,494.7	$ 2,055.2
Other revenue	16.9	25.6
Total revenue	2,511.6	2,080.8
Expenses:
Cost of goods sold (excluding amortization of acquired intangible assets)	105.9	104.0
Research and development	733.2	506.0
Selling, general and administrative	543.0	529.2
Amortization of acquired intangible assets	91.8	63.6
Acquisition related charges and restructuring, net	36.2	19.0
Total costs and expenses	1,510.1	1,221.8
Operating income	1,001.5	859.0
Other income and (expense):
Interest and investment income, net	6.8	9.0
Interest (expense)	(121.9)	(49.2)
Other income (expense), net	35.2	8.3
Income before income taxes	921.6	827.1
Income tax provision	120.9	108.2
Net income	$ 800.7	$ 718.9
Net income per common share:
Basic (in dollars per share)	$ 1.03	$ 0.90
Diluted (in dollars per share)	$ 0.99	$ 0.86
Weighted average shares:
Basic (in shares)	780.6	798.9
Diluted (in shares)	807.7	834.1