Share-Based Compensation (Components of Compensation Expense) (Details) - USD ($) $ in Millions	12 Months Ended
Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Stock-Based Compensation
Total share-based compensation expense	$ 576.6	$ 447.6	$ 325.8
Tax benefit related to share-based compensation expense	161.2	129.3	94.5
Reduction in income	415.4	318.3	231.3
Non-qualified stock options
Stock-Based Compensation
Total share-based compensation expense	346.1	276.3	197.6
Cost of goods sold
Stock-Based Compensation
Total share-based compensation expense	31.7	26.2	18.5
Research and development
Stock-Based Compensation
Total share-based compensation expense	250.7	196.5	144.7
Selling, general and administrative
Stock-Based Compensation
Total share-based compensation expense	$ 294.2	$ 224.9	$ 162.6

Represents the expense recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SAB TOPIC 14.F)
-URI http://asc.fasb.org/extlink&oid=27013229&loc=d3e301413-122809

Reference 2: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 1
-Subparagraph (b)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5047-113901

Reference 3: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 718
-SubTopic 10
-Section 50
-Paragraph 2
-Subparagraph (h)(1)(i)
-URI http://asc.fasb.org/extlink&oid=6415400&loc=d3e5070-113901

Reference 4: http://www.xbrl.org/2003/role/presentationRef
-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 14
-Section F

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The amount of expense, net of income tax, recognized during the period arising from equity-based compensation arrangements (for example, shares of stock, unit, stock options or other equity instruments) with employees, directors and certain consultants qualifying for treatment as employees.

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The total recognized tax benefit related to compensation cost for equity-based payment arrangements recognized in income during the period.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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