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Quarterly Results of Operations (Unaudited) (Details) - USD ($)
$ / shares in Units, shares in Millions, $ in Millions
3 Months Ended 12 Months Ended
Dec. 31, 2015
Sep. 30, 2015
Jun. 30, 2015
Mar. 31, 2015
Dec. 31, 2014
Sep. 30, 2014
Jun. 30, 2014
Mar. 31, 2014
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Quarterly Financial Data [Abstract]                      
Total revenue $ 2,563.3 $ 2,334.1 $ 2,277.8 $ 2,080.8 $ 2,085.5 $ 1,982.2 $ 1,872.7 $ 1,730.0 $ 9,256.0 $ 7,670.4 $ 6,493.9
Gross profit 2,433.8 2,202.7 2,153.3 1,951.2 1,951.7 1,859.1 1,745.7 1,621.4 8,741.0 7,177.9  
Income tax provision 184.5 14.2 114.6 108.2 96.9 69.0 109.0 52.6 421.5 327.5 215.5
Net income $ 561.0 $ (34.1) $ 356.2 $ 718.9 $ 613.9 $ 508.5 $ 597.8 $ 279.7 $ 1,602.0 $ 1,999.9 $ 1,449.9
Net income per share attributable to Celgene                      
Basic (in dollars per share) $ 0.71 $ (0.04) $ 0.45 $ 0.90 $ 0.77 $ 0.64 $ 0.75 $ 0.34 $ 2.02 $ 2.49 $ 1.75
Diluted (in dollars per share) $ 0.69 $ (0.04) $ 0.43 $ 0.86 $ 0.74 $ 0.61 $ 0.72 $ 0.33 $ 1.94 $ 2.39 $ 1.68
Weighted average shares:                      
Basic (in shares) 785.8 791.1 793.0 798.9 800.2 799.6 799.6 811.5 792.2 802.7 827.7
Diluted (in shares) 816.5 791.1 825.3 834.1 834.6 832.8 831.0 845.1 824.9 836.0 860.6