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Collaboration Agreements (Narrative) (Details)
shares in Millions
1 Months Ended 3 Months Ended 9 Months Ended
Mar. 26, 2015
USD ($)
Mar. 21, 2014
USD ($)
Collaborative_Arrangement
Mar. 21, 2014
Sep. 30, 2015
USD ($)
Jul. 31, 2015
USD ($)
option_target
Jun. 30, 2015
USD ($)
shares
Apr. 30, 2015
USD ($)
Feb. 28, 2015
USD ($)
Dec. 31, 2014
USD ($)
Sep. 30, 2015
USD ($)
Sep. 30, 2014
USD ($)
Sep. 30, 2015
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Sep. 30, 2014
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bluebird                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                       $ 9,000,000 $ 0
Milestone payments made                       0 0
Payment to terminate a collaboration agreement                       0 0
bluebird | Discovery and Development Collaboration and License Agreement                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Potential milestones payment                 $ 20,000,000.0     120,000,000  
bluebird | AG-881                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Potential milestones payment             $ 70,000,000            
Milestone payment, payable             10,000,000            
bluebird | AG-881 | Research and Development Collaboration Expense                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable             9,000,000.0            
Epizyme                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                   $ 0 $ 0 0 0
Milestone payments made                   0 0 0 0
Payment to terminate a collaboration agreement                   10,000,000 0 10,000,000 0
License payments FORMA                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Potential milestones payment                       $ 430,000,000.0  
FORMA                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Collaboration agreement, term     3 years 6 months                    
Research and development period                       4 years  
Upfront Fees                       $ 39,000,000 225,000,000
Milestone payments made                       0 0
Payment to terminate a collaboration agreement                       0 0
FORMA | Research and development payments                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Potential milestones payment                       200,000,000  
FORMA | Regulatory approval                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Potential milestones payment                       315,000,000.0  
FORMA | First Collaboration Agreement, First Ex-US License                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees               $ 19,000,000.0          
FORMA | Second Collaboration Agreement                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees   $ 225,000,000.0                      
Term of additional agreement   2 years                      
Payment to exercise additional agreements   $ 375,000,000                      
FORMA | Second Collaboration Agreement | Maximum                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Number of additional agreement | Collaborative_Arrangement   2                      
FORMA | Second Collaboration Agreement, First Ex-US License                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees             20,000,000.0            
MorphoSys                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                       0 0
Milestone payments made                       0 0
Payment to terminate a collaboration agreement $ 8,100,000                     8,100,000 0
Other Collaboration Arrangements                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                   26,900,000 6,000,000 47,900,000 54,000,000
Milestone payments made                   0 6,800,000 8,000,000 7,300,000
Payment to terminate a collaboration agreement                   $ 0 $ 0 0 0
Acceleron                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                       0 0
Milestone payments made                       0 0
Payment to terminate a collaboration agreement                       0 0
NantBioScience                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                       0 50,000,000
Milestone payments made                       0 0
Payment to terminate a collaboration agreement                       0 0
NantBioScience | Selling, general and administrative                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Upfront Fees                         $ 25,000,000
Collaboration and License Agreement | Epizyme | HMT Inhibitor Targeting Option Targets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable         $ 10,000,000.0                
Option targets | option_target         3                
Exclusive licenses | option_target         2                
Development milestone payment         $ 75,000,000.0                
Regulatory milestone payment         365,000,000.0                
Sales milestone payment         170,000,000.0                
Collaboration and License Agreement | Epizyme | DOT1L Program                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Regulatory milestone payment         100,000,000.0                
Additional development milestone payments         $ 35,000,000.0                
Collaboration and License Agreement | Epizyme | Molecule HMT Inhibitor Targeting DOT1L                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Research and development period         3 years                
Termination agreement, period         120 days                
Collaboration Agreement | Epizyme | B-Cell Maturation Antigen (BCMA)                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Contingent consideration           $ 230,000,000.0              
Milestone payment, payable           $ 25,000,000              
Termination agreement, period           90 days              
Co-development agreement           0.50              
Collaboration Agreement | Nurix, Inc | Immune Modulator Assets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable       $ 149,800,000                  
Research and Development Arrangement, Contract to Perform for Others, Equity Investment       $ 17,000,000                  
Research and development arrangement, contract to perform for others, equity interest       13                  
Research and development arrangement contract to perform for others, period after delivery of phase I data package       45 days                  
Research and development arrangement, contract to perform for others, future success-based milestone payments       $ 405,000,000                  
Research and development arrangement, contract to perform for others, agreement term       4 years                  
Strategic Collaboration Agreement | MedImmune Limited | MEDI4736                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable             $ 450,000,000            
Termination agreement, period             9 years            
Research and development arrangement, contract to perform for others, cost sharing percentage, period two             7500.00%            
Research and development arrangement, contract to perform for others, royalty rate, percentage of worldwide sales             7000.00%            
Research and development arrangement, contract to perform for others, final royalty rate             5000.00%            
Research and development arrangement, contract to perform for others, royalty rate, period to reach final rate             4 years            
Collaboration and Option Agreement | Sutro | Immune Modulator Assets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           $ 82,500,000              
Research and development arrangement, contract to perform for others, future success-based milestone payments           $ 190,000,000.0              
Termination agreement, period           6 months              
Research and development arrangement, contract to perform for others, agreement term           3 years              
Collaboration and Option Agreement | Sutro | Immune Modulator Assets | Research and Development Collaboration Expense                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           $ 69,500,000              
Collaboration and Option Agreement | Acetylon | Attainment of Developmental, Regulatory and Sales Milestones [Member]                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Research and development arrangement, contract to perform for others, future success-based milestone payments                       $ 120,000,000.0  
Collaboration and Investment Agreement | Juno Therapeutics, Inc | Development and Commercialization of Immuno-Therapeutics                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           150,000,000              
Research and development arrangement, contract to perform for others, premium paid on equity investment           $ 425,100,000              
Termination agreement, period           120 days              
Research and development arrangement, contract to perform for others, agreement term           10 years              
Research and development arrangement, contract to perform for others, cost and profit sharing percentage, agreement owner           70              
Research and development arrangement, contract to perform for others, cost and profit sharing percentage, counterparty           30              
Research and development arrangement, investment in counterparty, consideration to be transferred           $ 1,000,000,000              
Research and development arrangement, contract to perform for others, shares of counterparty common stock | shares           9.1              
Research and development arrangement, contract to perform for others, percentage of counterparty common stock           0.09              
Reserach and Development Arrangement Investment in Counterparty, Value of Shares           $ 424,900,000              
Manufacturing Rights Asset | bluebird | AG-881                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable             $ 1,000,000.0            
Noncurrent Assets | Collaboration and Option Agreement | Sutro | Immune Modulator Assets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           13,000,000              
Equity Investment Asset | Collaboration and Option Agreement | Sutro | Immune Modulator Assets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           10,000,000              
Option to license | Collaboration and Option Agreement | Sutro | Immune Modulator Assets                          
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]                          
Milestone payment, payable           $ 3,000,000