Collaboration Agreements (Tables)

9 Months Ended

Sep. 30, 2015

Collaboration Agreements [Abstract]

Schedule of Collaboration Agreements

A financial summary of certain period activity related to our collaboration agreements is presented below^1,2:

		Three-Month Periods Ended September 30,
		Research and Development Expense
		Upfront Fees	Milestones	Extension/Termination of Agreements	Amortization of Prepaid Research and Development	Equity Investments Made During Period
Acetylon	2015	$—	$—	$—	$5.4	$—
	2014	—	—	—	4.3	—
bluebird	2015	—	—	—	2.1	—
	2014	—	—	—	0.1	—
Epizyme	2015	—	—	10.0	—	—
	2014	—	—	—	—	—
Juno	2015	575.1	—	—	—	424.9
Nurix	2015	149.8	—	—	—	17.0
Sutro	2015	—	—	—	1.4	—
	2014	72.6	—	—	0.1	11.9
Other Collaboration Arrangements	2015	26.9	—	—	—	—
	2014	6.0	6.8	—	0.4	27.0

		Nine-Month Periods Ended September 30,
		Research and Development Expense
		Upfront Fees	Milestones	Extension/Termination of Agreements	Amortization of Prepaid Research and Development	Equity Investments Made During Period
Acceleron	2015	$—	$—	$—	$—	$—
	2014	—	—	—	—	52.4
Acetylon	2015	—	—	—	14.6	—
	2014	—	—	—	11.4	—
Agios	2015	9.0	—	—	—	—
	2014	—	—	—	—	13.0
AstraZeneca	2015	450.0	—	—	—	—
bluebird	2015	—	—	—	2.8	—
	2014	—	—	—	0.1	—
Epizyme	2015	—	—	10.0	—	—
	2014	—	—	—	—	9.9
FORMA	2015	39.0	—	—	—	—
	2014	225.0	—	—	0.1	—
Juno	2015	575.1	—	—	—	424.9
Lycera	2015	69.5	—	—	—	10.0
MorphoSys	2015	—	—	8.1	—	—
	2014	—	—	—	—	—
NantBioScience(3)	2015	—	—	—	—	—
	2014	50.0	—	—	—	90.0
Nurix	2015	149.8	—	—	—	17.0
Sutro	2015	—	—	—	3.4	—
	2014	72.6	—	—	0.2	11.9
Other Collaboration Arrangements	2015	47.9	8.0	—	0.9	50.0
	2014	54.0	7.3	—	6.9	47.9

A financial summary of the period-end balances related to our collaboration agreements is presented below:

	Balances as of:	Intangible Asset Balance	Equity Investment Balance	Percentage of Outstanding Equity
Acceleron	September 30, 2015	$—	$114.8	14%
	December 31, 2014	—	179.7	14%
Acetylon	September 30, 2015	5.8	25.0	11%
	December 31, 2014	20.4	25.0	10%
Agios	September 30, 2015	1.0	370.1	13%
	December 31, 2014	—	587.4	14%
bluebird	September 30, 2015	22.3	N/A	N/A
	December 31, 2014	0.1	N/A	N/A
Epizyme	September 30, 2015	—	47.3	8%
	December 31, 2014	—	69.3	11%
FORMA	September 30, 2015	0.1	N/A	N/A
	December 31, 2014	0.1	N/A	N/A
Juno	September 30, 2015	—	371.8	9%
Lycera	September 30, 2015	3.0	10.0	8%
MorphoSys	September 30, 2015	—	53.1	3%
	December 31, 2014	—	73.9	3%
NantBioScience	September 30, 2015	—	90.0	13%
	December 31, 2014	—	90.0	14%
Nurix	September 30, 2015	0.2	17.0	13%
Sutro	September 30, 2015	24.4	17.6	15%
	December 31, 2014	12.8	17.6	15%
Other Collaboration Arrangements	September 30, 2015	22.1	130.1	N/A
	December 31, 2014	34.4	90.8	N/A

¹  Activity and balances are presented specifically for notable new collaborations and for those collaborations which we have described in detail in our 2014 Annual Report on Form 10-K if there has been new significant activity during the periods presented. Amounts related to collaborations that are not specifically described are presented in the aggregate as Other Collaboration Arrangements.

²  In addition to the expenses noted in the tables above, we may also incur expenses for collaboration agreement related activities that are managed or funded by us.

³  $25.0 million of expense related to the settlement of contingent matching contributions was also recognized at the 2014 inception of the collaboration agreement with NantBioScience and included in Selling, General and Administrative expense.