Share-Based Compensation (Tables)

6 Months Ended

Jun. 30, 2012

Share-Based Compensation

Components of share-based compensation expense

	Three-Month Periods Ended				Six-Month Periods Ended
	June 30,				June 30,
	2012		2011		2012		2011
Cost of goods sold	$	2,983	$	2,419	$	5,859	$	4,427
Research and development	23,556		22,880		48,584		55,472
Selling, general and administrative	27,075		25,613		53,891		48,706
Total share-based compensation expense	53,614		50,912		108,334		108,605
Tax benefit related to share-based compensation expense
	14,117		12,417		28,736		27,869
Reduction in income	$	39,497	$	38,495	$	79,598	$	80,736

Summary of activity for stock options, RSUs and PSUs

				Performance-
			Restricted	Based Restricted
	Stock		Stock	Stock
	Options		Units	Units
Outstanding at December 31, 2011	44,526,748		3,019,943	28,500
Changes during the Year:
Granted	4,804,055		1,534,372	-
Exercised / Released	(5,407,630	)	(389,874)	-
Forfeited	(687,456	)	(85,975)	(1,500)
Expired	(46,016	)	N/A	N/A
Outstanding at June 30, 2012	43,189,701		4,078,466	27,000

Schedule of total compensation cost related to nonvested awards not yet recognized and weighted-average periods over which awards are expected to be recognized

			Restricted		Performance-
	Stock		Stock		Based Restricted
	Options		Units		Stock Units
Unrecognized compensation cost	$	285,062	$	180,670	$	1,004
Expected weighted-average period in years of compensation cost to be recognized	2.3		2.1		1.5