Share-Based Compensation (Tables)

3 Months Ended

Mar. 31, 2012

Share-Based Compensation

Components of share-based compensation expense

	Three-Month Periods Ended March 31,
	2012		2011
Cost of good sold	$	2,876	$	2,008
Research and development		25,028		32,592
Selling, general and administrative		26,816		23,093
Total share-based compensation expense		54,720		57,693
Tax benefit related to share-based compensation expense		14,619		15,452
Reduction in income	$	40,101	$	42,241

Summary of activity for stock options, RSUs and PSUs

			Performance-
		Restricted	Based Restricted
	Stock	Stock	Stock
	Options	Units	Units
Outstanding at December 31, 2011	44,526,748	3,019,943	28,500
Changes during the Year:
Granted	2,398,800	71,963	-
Exercised / Released	(4,672,377)	(48,750)	-
Forfeited	(242,178)	(27,530)	(1,500)
Expired	(21,537)	N/A	N/A
Outstanding at March 31, 2012	41,989,456	3,015,626	27,000

Schedule of total compensation cost related to nonvested awards not yet recognized and weighted-average periods over which awards are expected to be recognized

			Restricted		Performance-
	Stock		Stock		Based Restricted
	Options		Units		Stock Units
Unrecognized compensation cost	$	282,769	$	91,000	$	1,181
Expected weighted-average period in years of compensation cost to be recognized	2.3		1.6		1.8