Share-Based Compensation (Details 2) (USD $)	12 Months Ended
	Dec. 31, 2011	Dec. 31, 2010	Dec. 31, 2009
Stock-Based Compensation
Allocated share-based compensation expense	$ 217,202,000	$ 182,796,000	$ 143,819,000
Tax benefit related to share-based compensation expense	55,900,000	42,362,000	32,400,000
Reduction in income	161,302,000	140,434,000	111,419,000
Share-based compensation cost included in inventory	2,000,000	2,400,000
Non-qualified stock options
Stock-Based Compensation
Allocated share-based compensation expense	154,400,000	142,600,000	117,000,000
Stock Options
Stock-Based Compensation
Unrecognized compensation cost	299,300,000
Weighted-average period over which unrecognized compensation cost is expected to be recognized (in years)	2.3
Cost of goods sold
Stock-Based Compensation
Allocated share-based compensation expense	9,762,000	6,776,000	4,444,000
Research and development expenses
Stock-Based Compensation
Allocated share-based compensation expense	104,704,000	82,097,000	64,751,000
Selling, general and administrative expenses
Stock-Based Compensation
Allocated share-based compensation expense	$ 102,736,000	$ 93,923,000	$ 74,624,000