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CONSOLIDATED STATEMENTS OF CASH FLOWS (USD $)
In Thousands, unless otherwise specified
12 Months Ended
Dec. 31, 2011
Dec. 31, 2010
Dec. 31, 2009
Cash flows from operating activities:      
Net income $ 1,317,456 $ 880,192 $ 776,747
Adjustments to reconcile net income to net cash provided by operating activities:      
Depreciation of long-term assets 71,153 54,234 41,682
Amortization 291,698 204,855 84,386
Allocation of pre-paid royalties 16,742 47,241 36,045
Provision (benefit) for accounts receivable allowances 6,354 (2,309) 2,664
Deferred income taxes (85,822) (103,923) (26,939)
Impairment of acquired in-process research and development 118,000    
Change in value of contingent consideration (147,463) 9,712  
Share-based compensation expense 225,154 186,989 145,929
Equity in losses of affiliated companies 2,804 1,928 518
Share-based employee benefit plan expense 20,664 14,403 11,515
Unrealized change in value of foreign currency forward contracts (47,611) 9,970 (9,738)
Realized (gain) on marketable securities available for sale (3,842) (11,531) (31,013)
Other, net (11,404) (2,352) 8,715
Change in current assets and liabilities, excluding the effect of acquisitions:      
Accounts receivable (263,130) (234,452) (122,615)
Inventory 70,980 18,723 1,540
Other operating assets (69,288) (45,674) (53,847)
Assets held for sale, net 2,361 2,999  
Accounts payable and other operating liabilities 223,814 51,557 652
Payment of contingent consideration (23,324)    
Income tax payable 95,326 78,110 39,823
Deferred revenue (1,937) 20,884 3,791
Net cash provided by operating activities 1,808,685 1,181,556 909,855
Cash flows from investing activities:      
Proceeds from sales of marketable securities available for sale 2,175,172 3,931,883 2,258,376
Purchases of marketable securities available for sale (1,693,380) (3,272,225) (3,007,673)
Payments for acquisition of business, net of cash acquired   (2,652,377)  
Proceeds from the sale of non-core assets, net 93,185    
Capital expenditures (132,119) (98,632) (93,384)
Investment in affiliated companies (3,914) (1,934) (3,603)
Purchases of investment securities (59,248) (14,020) (13,127)
Other investing activities (2,000)   3,333
Net cash provided by (used in) investing activities 377,696 (2,107,305) (856,078)
Cash flows from financing activities:      
Payment for treasury shares (2,221,157) (183,116) (209,461)
Proceeds from short-term borrowing 1,878,784    
Principal repayments on short-term borrowing (1,353,061)    
Payment of contingent consideration (156,676)    
Proceeds from issuance of long-term debt   1,237,270  
Net proceeds from exercise of common stock options and warrants 166,451 86,889 49,751
Excess tax benefit from share-based compensation arrangements 31,054 36,124 97,838
Net cash provided by (used in) financing activities (1,654,605) 1,177,167 (61,872)
Effect of currency rate changes on cash and cash equivalents (23,440) (2,462) 17,881
Net increase in cash and cash equivalents 508,336 248,956 9,786
Cash and cash equivalents at beginning of period 1,351,128 1,102,172 1,092,386
Cash and cash equivalents at end of period 1,859,464 1,351,128 1,102,172
Supplemental schedule of non-cash investing and financing activity:      
Change in net unrealized (gain) loss on marketable securities available for sale (3,651) (13,808) (3,326)
Matured shares tendered in connection with stock option exercises (4,912) (8,245) (2,014)
Supplemental disclosure of cash flow information:      
Interest paid 2,346 1,752 1,882
Income taxes paid $ 93,019 $ 121,976 $ 70,539