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Consolidated Statements of Cash Flows (Unaudited) (USD $)
In Thousands
6 Months Ended
Jun. 30, 2011
Jun. 30, 2010
Cash flows from operating activities:    
Net income $ 534,294 $ 389,794
Adjustments to reconcile net income to net cash provided by operating activities:    
Depreciation of long-term assets 35,019 25,470
Amortization 140,249 89,224
Allocation of pre-paid royalties 15,744 24,467
Provision (benefit) for accounts receivable allowances 1,405 (1,718)
Deferred income taxes (85,282) (34,933)
Impairment of acquired in-process research and development 118,000  
Change in value of contingent consideration (111,169) 10,754
Share-based compensation expense 112,097 86,571
Equity in (gains) losses of affiliated companies (695) (638)
Share-based employee benefit plan expense 8,071 6,904
Unrealized change in value of foreign currency forward contracts 8,874 17,640
Realized (gain) loss on marketable securities available for sale 1,455 (6,018)
Other, net 2,016 2,820
Change in current assets and liabilities, excluding the effect of acquisitions:    
Accounts receivable (126,187) (73,020)
Inventory 65,428 927
Other operating assets 12,952 37,378
Assets held for sale, net 1,290  
Accounts payable and other operating liabilities (35,551) 15,539
Income tax payable 43,526 (258)
Deferred revenue (5,137) 4,148
Net cash provided by operating activities 736,399 595,051
Cash flows from investing activities:    
Proceeds from sales of marketable securities available for sale 1,095,497 2,037,313
Purchases of marketable securities available for sale (963,293) (2,420,620)
Payments for acquisition of business, net of cash acquired   (337,608)
Proceeds from the sale of non-core assets, net 93,185  
Capital expenditures (53,048) (40,238)
Investment in affiliated companies (2,329) (1,466)
Purchases of investment securities (533) (13,562)
Net cash provided by (used in) investing activities 169,479 (776,181)
Cash flows from financing activities:    
Payment for treasury shares (689,126) (105,436)
Net proceeds from exercise of common stock options and warrants 54,357 44,996
Excess tax benefit from share-based compensation arrangements 10,462 15,938
Net cash provided by (used in) financing activities (624,307) (44,502)
Effect of currency rate changes on cash and cash equivalents 15,345 (20,932)
Net increase (decrease) in cash and cash equivalents 296,916 (246,564)
Cash and cash equivalents at beginning of period 1,351,128 1,102,172
Cash and cash equivalents at end of period 1,648,044 855,608
Supplemental schedule of non-cash investing and financing activity:    
Contingent consideration issued in acquisition of Gloucester   230,201
Change in net unrealized (gain) loss on marketable securities available for sale (4,804) (15,172)
Matured shares tendered in connection with stock option exercises   (163)
Supplemental disclosure of cash flow information:    
Interest paid 2,016 1,638
Income taxes paid $ 66,689 $ 83,342