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Condensed Consolidated Statements of Cash Flows - USD ($)
3 Months Ended
Mar. 31, 2025
Mar. 31, 2024
Operating activities:    
Net loss $ (3,236,763) $ (1,915,327)
Adjustments to reconcile net loss to net cash used in operating activities:    
Amortization and depreciation 608 1,588
Non-cash lease expense 31,867 29,265
Share-based compensation 63,599 59,961
Issuance of common stock to vendors for services 30,000  
Change in fair value of convertible debt   (165,382)
Change in operating assets and liabilities:    
Contracts and grants receivable   54,225
Prepaid expenses and other current assets 605,534 414,138
Research and development incentives receivable   17,379
Operating lease liability (32,737) (29,359)
Accounts payable and accrued expenses 976,785 391,929
Accrued compensation (285,905) (200,899)
Net cash flows from operating activities (1,847,012) (1,342,482)
Financing activities:    
Proceeds from issuance of common stock pursuant to At Market Issuance Sales Agreement 2,697,542  
Issuance costs associated with public offerings   (8,992)
Convertible debt repayments (1,372,873)  
Net cash flows from financing activities 1,324,669 (8,992)
Effect of exchange rate on cash and cash equivalents   (3,136)
Net decrease in cash and cash equivalents (522,343) (1,354,610)
Cash and cash equivalents at beginning of year 7,819,514 8,446,158
Cash and cash equivalents at end of year 7,297,171 7,091,548
Supplemental information:    
Cash paid for state income taxes 56,169 17,965
Cash paid for interest 35,044 64,047
Cash paid for lease liabilities:    
Operating lease 34,875 34,100
Non-cash investing and financing activities:    
Pontifax conversion of portion of debt principal into common stock   99,416
Deferred issuance cost reclassified to additional paid-in capital $ 60,011  
Offering costs included in accounts payable   $ 123,689