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Condensed Consolidated Statements of Changes in Shareholders' Equity/(Deficit) - USD ($)
Preferred Stock
Series D Preferred Stock
Common Stock
B Riley Sales Agreement [Member]
Common Stock
Public Offering
Common Stock
Additional Paid-In Capital
B Riley Sales Agreement [Member]
Additional Paid-In Capital
Series D Preferred Stock
Additional Paid-In Capital
Public Offering
Additional Paid-In Capital
Accumulated Other Comprehensive Income (Loss)
Accumulated Deficit
B Riley Sales Agreement [Member]
Series D Preferred Stock
Public Offering
Total
Balance at Dec. 31, 2021       $ 179       $ 216,445,584 $ 41,942 $ (205,765,107)       $ 10,722,598
Balance (in shares) at Dec. 31, 2021       178,744                    
Balance at Dec. 31, 2021 $ 0                          
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement   $ 1     $ 79,353           $ 79,354      
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)   539                        
Issuance costs         (2,593)           (2,593)      
Declaration of Series D preferred stock 43                          
Declaration of Series D preferred stock           $ (43)           $ (43)    
Fractional shares issued in reverse stock split (Shares)       1,222                    
Fractional shares issued in reverse stock split       $ 1       (1)            
Issuance of common stock to vendors       $ 1       212,002           212,003
Issuance of common stock to vendors (in shares)       1,393                    
Share-based compensation expense               333,389           333,389
Foreign currency translation adjustment                 (17,195)         (17,195)
Net loss                   (13,798,339)       (13,798,339)
Balance at Dec. 31, 2022       $ 182       217,067,691 24,747 (219,563,446)       (2,470,826)
Balance (in Shares) at Dec. 31, 2022       181,898                    
Balance at Dec. 31, 2022 43                         43
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement       $ 1       70,729           70,730
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)       1,329                    
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement               (2,341)           (2,341)
Declaration of Series D preferred stock (43)                          
Share-based compensation expense               73,634           73,634
Foreign currency translation adjustment                 (12,153)         (12,153)
Net loss                   (1,046,109)       (1,046,109)
Balance at Mar. 31, 2023       $ 183       217,209,713 12,594 (220,609,555)       (3,387,065)
Balance (in Shares) at Mar. 31, 2023       183,227                    
Balance at Dec. 31, 2022       $ 182       217,067,691 24,747 (219,563,446)       (2,470,826)
Balance (in shares) at Dec. 31, 2022       181,898                    
Balance at Dec. 31, 2022 43                         43
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement   $ 53     3,091,409           3,091,462      
Sale of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)   53,202                        
Issuance costs         $ (113,217)   $ (834,061)       $ (113,217)   $ (834,061)  
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering     $ 144       $ 8,495,673           $ 8,495,817  
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering (in shares)     143,844                      
Declaration of Series D preferred stock (43)                          
Issuance of common stock to vendors       $ 3       72,997           73,000
Issuance of common stock to vendors (in shares)       3,125                    
Issuance of common stock associated with conversion of debt       $ 265       3,034           3,299
Issuance of common stock associated with conversion of debt (in shares)       264,714                    
Issuance of common stock for unexercised purchase option       $ 2       49,998           50,000
Issuance of common stock for unexercised purchase option (in shares)       1,978                    
Share-based compensation expense               370,182           370,182
Foreign currency translation adjustment                 (2,504)         (2,504)
Net loss                   (6,140,730)       (6,140,730)
Balance at Dec. 31, 2023       $ 649       228,203,706 22,243 (225,704,176)       2,522,422
Balance (in Shares) at Dec. 31, 2023       648,761                    
Balance at Dec. 31, 2023 $ 0                          
Issuance of common stock associated with conversion of debt       $ 9       99,407           99,416
Issuance of common stock associated with conversion of debt (in shares)       9,139                    
Share-based compensation expense               59,961           59,961
Foreign currency translation adjustment                 1,900         1,900
Net loss                   (1,915,327)       (1,915,327)
Balance at Mar. 31, 2024       $ 658       $ 228,363,074 $ 24,143 $ (227,619,503)       $ 768,372
Balance (in Shares) at Mar. 31, 2024       657,900