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Nature of Business (Details)
3 Months Ended 9 Months Ended 12 Months Ended
Nov. 06, 2023
USD ($)
$ / shares
shares
May 09, 2023
USD ($)
$ / shares
shares
May 02, 2023
$ / shares
shares
Apr. 27, 2023
shares
Feb. 10, 2023
Feb. 09, 2023
shares
Nov. 07, 2022
shares
Oct. 04, 2022
shares
Aug. 05, 2022
shares
Feb. 07, 2022
shares
Sep. 29, 2021
shares
Sep. 30, 2023
USD ($)
shares
Sep. 30, 2022
USD ($)
Sep. 30, 2023
USD ($)
segment
shares
Sep. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
segment
shares
Dec. 31, 2021
USD ($)
shares
Mar. 22, 2023
USD ($)
Dec. 31, 2020
USD ($)
Nature of business:                                      
Number of operating segments | segment                           2   2      
Accumulated deficit                       $ (223,884,281)   $ (223,884,281)   $ (219,563,446) $ (205,765,107)    
Net loss                       (1,662,702) $ (3,309,003) (4,320,835) $ (10,044,784) (13,798,339) (12,550,973)    
Net cash used in operating activities                           (6,775,896) (9,021,880) (12,649,021) (11,739,620)    
Reclassification of convertible debt from current to non-current liability                               1,416,463      
Number of shares sold                           3,091,462   79,354 19,705,647    
Cash and cash equivalents                       10,298,534 16,865,642 10,298,534 16,865,642 13,359,615 26,043,897   $ 18,676,663
Net decrease in cash                           $ 3,061,081 9,178,255 $ 12,684,282 (7,367,234)    
Percentage change in cash and cash equivalent                           23.00%   49.00%      
Accumulated deficit                       223,884,281   $ 223,884,281   $ 219,563,446 205,765,107    
Working capital                       5,450,322   5,450,322   (2,663,721) 20,278,345    
Working capital increase, decrease                           $ (8,114,043)   2,663,721 $ (22,942,066)    
Working capital increase (decrease) as a percent                           305.00%     113.00%    
Government grant funding                       $ 66,051   $ 66,051   $ 115,130 $ 138,889    
Common Stock, Shares, Issued | shares                       10,378,238   10,378,238   2,908,578 2,858,244    
Number of shares issued | shares       50,000     5,129 1,667 3,664 5,377 1,667                
Reverse stock spilt effective from February 10, 2023         0.067 0.067                          
Fractional shares issue under reverse stock split | shares           0                          
Repayment of debt principal                           $ 7,000,000          
Consideration paid recorded in general and administrative expense                       $ 973,040 $ 1,326,249 3,098,949 $ 5,250,510 $ 6,692,904 $ 5,008,738    
Issuance of common stock in connection with Silk Roads purchase option                           50,000          
Public Offering                                      
Nature of business:                                      
Proceeds from Issuance of Common Stock   $ 8,500,000                                  
Shares issued price per share | $ / shares   $ 1.30                                  
Exercise price of warrants | $ / shares   $ 0.001                                  
Expiration term of warrants   5 years                                  
At Market Issuance Sales Agreement                                      
Nature of business:                                      
Proceeds from Issuance of Common Stock                           7,700,000          
Number of shares sold                           3,000,000.0          
Common Stock                                      
Nature of business:                                      
Number of shares sold                           $ 851   8 $ 812    
Issuance of common stock in connection with Silk Roads purchase option (in shares) | shares                           31,646          
Issuance of common stock in connection with Silk Roads purchase option                           $ 32          
Common Stock | Public Offering                                      
Nature of business:                                      
Shares issued price per share | $ / shares   $ 1.30                                  
Number of shares issued | shares   2,301,500                                  
Exercise price of warrants | $ / shares   $ 1.50                                  
Subsequent Event                                      
Nature of business:                                      
Reverse stock spilt effective from February 10, 2023         0.067 0.067                          
Pre-funded warrants | Public Offering                                      
Nature of business:                                      
Number of common warrants to purchase shares issued | shares   4,237,000                                  
Common warrants | Public Offering                                      
Nature of business:                                      
Number of common warrants to purchase shares issued | shares   6,538,500                                  
Exercise price of warrants | $ / shares   $ 1.50                                  
CiVax                                      
Nature of business:                                      
Revenue from collaborative arrangement                           $ 1,500,000   $ 1,500,000      
Term (in years)                           P2Y   two years      
HyBryte                                      
Nature of business:                                      
Revenue from collaborative arrangement                           $ 1,100,000   $ 1,100,000      
Term (in years)                           P4Y   four years      
NIH                                      
Nature of business:                                      
Government grant funding                       $ 1,000,000.0   $ 1,000,000.0   $ 1,700,000      
DTRA | Contract revenue                                      
Nature of business:                                      
Revenue from collaborative arrangement                               $ 600,000      
Term (in years)                               three years      
Exclusive option agreement | Silk Road                                      
Nature of business:                                      
Consideration paid recorded in general and administrative expense                           $ 50,000          
Exclusive option agreement | Common Stock                                      
Nature of business:                                      
Shares issued price per share | $ / shares     $ 1.58                                
Number of shares issued | shares     31,646                                
Exclusive option agreement | Common Stock | Silk Road                                      
Nature of business:                                      
Issuance of common stock in connection with Silk Roads purchase option (in shares) | shares                           31,646          
Issuance of common stock in connection with Silk Roads purchase option                           $ 50,000          
B Riley Sales Agreement [Member] | Underwritten public offering                                      
Nature of business:                                      
Maximum Percentage Of Shares Available For Sale Of Market Value 33.33%                                    
B Riley Sales Agreement [Member] | Subsequent Event                                      
Nature of business:                                      
Proceeds from Issuance of Common Stock $ 3,091,462                                    
Common stock available for sale (in Dollars) $ 23,600,000                                 $ 26,600,000  
Maximum Percentage Of Shares Available For Sale Of Market Value 33.33%                                    
Shares issued price per share | $ / shares $ 3.63                                    
Common Stock, Shares, Issued | shares 851,130