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Condensed Consolidated Balance Sheets - USD ($)
Sep. 30, 2023
Jun. 30, 2023
Dec. 31, 2022
Sep. 30, 2022
Jun. 30, 2022
Dec. 31, 2021
Dec. 31, 2020
Current assets:              
Cash and cash equivalents $ 10,298,534   $ 13,359,615 $ 16,865,642   $ 26,043,897 $ 18,676,663
Contracts and grants receivable 66,051   115,130     138,889  
Research and development incentives receivable, current 22,852   104,198     103,832  
Prepaid expenses and other current assets 584,438   274,209     282,903  
Total current assets 10,971,875   13,853,152     26,569,521  
Security deposit 22,777   22,777     22,777  
Office furniture and equipment, net of accumulated depreciation of $119,730 and $114,766 13,517   18,481     22,220  
Deferred issuance cost 17,867   20,206     20,266  
Right-of-use lease assets 258,487   340,987     106,155 222,445
Research and development incentives receivable, net of current portion 18,306   24,114     121,238  
Other assets           7,750  
Total assets 11,302,829   14,279,717     26,869,927  
Current liabilities:              
Accounts payable 1,460,715   3,865,796     2,925,544  
Accrued expenses 2,386,836   2,307,746     2,956,545  
Accrued compensation 55,543   336,692     302,936  
Lease liabilities, current 118,459   108,948     106,151  
Convertible debt, net of debt discount of $0 and $102,309 1,500,000   9,897,691        
Total current liabilities 5,521,553   16,516,873     6,291,176  
Non-current liabilities:              
Convertible debt 1,416,463   0     9,856,153  
Lease liabilities, net of current portion 143,658   233,627        
Total liabilities 7,081,674   16,750,500     16,147,329  
Commitments and contingencies        
Series D preferred stock, $.001 par value; 0 and 50,000 shares authorized, none issued or outstanding as of September 30, 2023 and December 31, 2022, respectively     43        
Shareholders' equity/(deficit):              
Preferred stock, 350,000 and 300,000 shares authorized as of September 30, 2023 and December 31, 2022, respectively; none issued or outstanding 0   0      
Common stock, $.001 par value; 75,000,000 shares authorized; 10,378,238 and 2,908,578 shares issued and outstanding at September 30, 2023 and December 31, 2022, respectively 10,378   2,909     2,859  
Additional paid-in capital 228,070,740   217,064,964     216,442,904  
Accumulated other comprehensive income 24,318   24,747     41,942  
Accumulated deficit (223,884,281)   (219,563,446)     (205,765,107)  
Total shareholders' equity/(deficit) 4,221,155 $ 5,800,200 (2,470,826) $ 1,032,002 $ 4,205,886 10,722,598 $ 3,741,828
Total liabilities, mezzanine equity and shareholders' equity/(deficit) $ 11,302,829   $ 14,279,717     $ 26,869,927