Consolidated Statements of Changes in Mezzanine Equity and Shareholders' Equity (Deficit) - USD ($)	Common Stock Pre-funded warrants	Common Stock	Additional Paid-In Capital B Riley Sales Agreement [Member]	Additional Paid-In Capital Public Offering	Additional Paid-In Capital Pre-funded warrants	Additional Paid-In Capital	Accumulated Other Comprehensive Income/Loss	Accumulated Deficit	B Riley Sales Agreement [Member]	Public Offering	Pre-funded warrants	Total
Balance at Dec. 31, 2021		$ 2,859				$ 216,442,904	$ 41,942	$ (205,765,107)				$ 10,722,598
Balance (in shares) at Dec. 31, 2021		2,858,244
Issuance of common stock to vendors		$ 11				99,990						100,001
Issuance of common stock to vendors (in shares)		11,788
Share-based compensation expense						149,941						149,941
Foreign currency translation adjustment							(30,873)					(30,873)
Net loss								(6,735,781)				(6,735,781)
Balance at Jun. 30, 2022		$ 2,870				216,692,835	11,069	(212,500,888)				4,205,886
Balance (in Shares) at Jun. 30, 2022		2,870,032
Balance at Mar. 31, 2022		$ 2,864				216,571,171	124,592	(210,114,128)				6,584,499
Balance (in shares) at Mar. 31, 2022		2,863,621
Issuance of common stock to vendors		$ 6				49,994						50,000
Issuance of common stock to vendors (in shares)		6,411
Share-based compensation expense						71,670						71,670
Foreign currency translation adjustment							(113,523)					(113,523)
Net loss								(2,386,760)				(2,386,760)
Balance at Jun. 30, 2022		$ 2,870				216,692,835	11,069	(212,500,888)				4,205,886
Balance (in Shares) at Jun. 30, 2022		2,870,032
Balance at Dec. 31, 2022		$ 2,909				217,064,964	24,747	(219,563,446)				(2,470,826)
Balance (in shares) at Dec. 31, 2022		2,908,578
Issuance costs associated with B. Riley At Market Issuance Sales Agreement		$ 851				3,090,611						3,091,462
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)		851,130
Issuance costs			$ (95,348)	$ (834,061)					$ (95,348)	$ (834,061)
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering		$ 2,301				8,493,516						8,495,817
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering (in shares)		2,301,500
Issuance of common stock to vendors		$ 50				72,950						73,000
Issuance of common stock to vendors (in shares)		50,000
Issuance of common stock upon exercise of pre-funded warrants	$ 3,699				$ (400)						$ 3,299
Issuance of common stock upon exercise of pre-funded warrants (in shares)	3,699,000
Issuance of common stock in connection with Silk Roads purchase option		$ 32				49,968						50,000
Issuance of common stock in connection with Silk Roads purchase option (in shares)		31,646
Share-based compensation expense						163,676						163,676
Foreign currency translation adjustment							(18,686)					(18,686)
Net loss								(2,658,133)				(2,658,133)
Balance at Jun. 30, 2023		$ 9,842				228,005,876	6,061	(222,221,579)				5,800,200
Balance (in Shares) at Jun. 30, 2023		9,841,854
Balance at Mar. 31, 2023		$ 2,930				217,206,966	12,594	(220,609,555)				(3,387,065)
Balance (in shares) at Mar. 31, 2023		2,929,773
Issuance costs associated with B. Riley At Market Issuance Sales Agreement		$ 830				3,019,902						3,020,732
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)		829,935
Issuance costs			$ (93,007)	$ (834,061)					$ (93,007)	$ (834,061)
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering		$ 2,301				8,493,516						8,495,817
Issuance of common stock and pre-funded warrants in connection with May 2023 public offering (in shares)		2,301,500
Issuance of common stock to vendors		$ 50				72,950						73,000
Issuance of common stock to vendors (in shares)		50,000
Issuance of common stock upon exercise of pre-funded warrants	$ 3,699				$ (400)						$ 3,299
Issuance of common stock upon exercise of pre-funded warrants (in shares)	3,699,000
Issuance of common stock in connection with Silk Roads purchase option		$ 32				49,968						50,000
Issuance of common stock in connection with Silk Roads purchase option (in shares)		31,646
Share-based compensation expense						90,042						90,042
Foreign currency translation adjustment							(6,533)					(6,533)
Net loss								(1,612,024)				(1,612,024)
Balance at Jun. 30, 2023		$ 9,842				$ 228,005,876	$ 6,061	$ (222,221,579)				$ 5,800,200
Balance (in Shares) at Jun. 30, 2023		9,841,854