Consolidated Statements of Cash Flows - USD ($)	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021
Operating activities:
Net loss	$ (13,798,339)	$ (12,550,973)
Adjustments to reconcile net loss to net cash used in operating activities:
Amortization and depreciation	24,562	34,161
Non-cash lease expense	112,714	116,290
Share-based compensation	333,389	361,559
Issuance of common stock to vendors for services	212,003	27,500
Amortization of deferred issuance costs associated with convertible debt	41,538	41,926
Gain on forgiveness of PPP loan		(421,584)
Change in operating assets and liabilities:
Licensing, contracts and grants receivable	23,759	64,885
Prepaid expenses and other current assets	8,694	(57,430)
Research and development incentives receivable	73,374	205,237
Operating lease liability	(111,122)	(116,290)
Accounts payable and accrued expenses	396,651	1,127,259
Accrued compensation	33,756	(572,160)
Net cash used in operating activities	(12,649,021)	(11,739,620)
Investing activities:
Purchases of office furniture and equipment	(13,073)	(11,789)
Net cash used in investing activities	(13,073)	(11,789)
Financing activities:
Proceeds from issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	79,354	19,705,647
Costs associated with B. Riley At Market Issuance Sales Agreement	(2,533)	(621,899)
Proceeds from the exercise of warrants		79
Proceeds from the exercises of stock options		25,835
Costs associated with issuance of convertible debt		(45,512)
Principal repayment - financing lease		(6,149)
Net cash provided by financing activities	76,821	19,058,001
Effect of exchange rate on cash and cash equivalents	(99,009)	60,642
Net (decrease)/increase in cash and cash equivalents	(12,684,282)	7,367,234
Cash and cash equivalents at beginning of period	26,043,897	18,676,663
Cash and cash equivalents at end of period	13,359,615	26,043,897
Supplemental information:
Cash paid for state income taxes	16,043	7,727
Cash paid for interest	857,411	668,715
Cash paid for lease liabilities:
Operating lease	133,300	133,300
Financing lease		6,408
Non-cash investing and financing activities:
Right-of-use assets and lease liabilities recorded	347,546
Deferred issuance cost reclassified to additional paid-in capital	60	$ 33,257
Declaration of Series D preferred stock	$ 43