Consolidated Statements of Changes in Mezzanine Equity and Shareholders' Equity - USD ($)	Common Stock	Additional Paid-In Capital	Accumulated Other Comprehensive Income/Loss	Accumulated Deficit	Total
Balance at Dec. 31, 2020	$ 2,043	$ 196,978,256	$ (24,337)	$ (193,214,134)	$ 3,741,828
Balance (in shares) at Dec. 31, 2020	2,042,911
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	$ 812	19,704,835			19,705,647
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)	811,646
Issuance costs associated with B. Riley At Market Issuance Sales Agreement		(655,156)			(655,156)
Issuance of common stock to vendors	$ 2	27,498			27,500
Issuance of common stock to vendors (in shares)	1,667
Exercise of common stock options	$ 2	25,833			$ 25,835
Exercise of common stock options (in shares)	2,018				2,018
Exercise of warrants		79			$ 79
Exercise of warrants (in shares)	2
Share-based compensation expense		361,559			361,559
Foreign currency translation adjustment			66,279		66,279
Net loss				(12,550,973)	(12,550,973)
Balance at Dec. 31, 2021	$ 2,859	216,442,904	41,942	(205,765,107)	10,722,598
Balance (in Shares) at Dec. 31, 2021	2,858,244
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement	$ 8	79,346			79,354
Issuance of common stock pursuant to B. Riley At Market Issuance Sales Agreement (in shares)	8,542
Issuance costs associated with B. Riley At Market Issuance Sales Agreement		(2,593)			(2,593)
Declaration of Series D preferred stock		(43)			(43)
Issuance of common stock in reverse stock split (Shares)	19,544
Issuance of common stock in reverse stock split	$ 20	(20)
Issuance of common stock to vendors	$ 22	211,981			212,003
Issuance of common stock to vendors (in shares)	22,248
Share-based compensation expense		333,389			333,389
Foreign currency translation adjustment			(17,195)		(17,195)
Net loss				(13,798,339)	(13,798,339)
Balance at Dec. 31, 2022	$ 2,909	$ 217,064,964	$ 24,747	$ (219,563,446)	$ (2,470,826)
Balance (in Shares) at Dec. 31, 2022	2,908,578