X0202 4 2005-12-12 0000812121 CRITICARE SYSTEMS INC /DE/ CMD 0001261294 BARNES JEFFREY T 222 BERKELEY ST. BOSTON MA 02116 1 0 0 0 Common Stock 2005-12-12 4 S 0 1401521 4.54 D 0 I Oxford Bioscience Partners III L.P. Common Stock 2005-12-12 4 S 0 199753 4.54 D 0 I Oxford Bioscience Partners (Bermuda) III L.P. Common Stock 2005-12-12 4 S 0 131181 4.54 D 0 I Oxford Bioscience Partners (Adjunct) III L.P. Common Stock 2005-12-12 4 S 0 16618 4.54 D 0 I mRNA Fund L.P. Common Stock 20000 D Securities held of record by Oxford Bioscience Partners III L.P. ("OBP"). Mr. Barnes (a general partner of OBP Management III L.P., the general partner of OBP) may be deemed to beneficially own the shares held of record by OBP. Mr. Barnes disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. Securities held of record by Oxford Bioscience Partners (Bermuda) III Limited Partnership ("OBP Bermuda") . Mr. Barnes (a general partner of OBP Management (Bermuda) III Limited Partnership, the general partner of OBP Bermuda) may be deemed to beneficially own the shares held of record by OBP Bermuda. Mr. Barnes disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. Securities held of record by Oxford Bioscience Partners (Adjunct) III L.P. ("OBP Adjunct"). Mr. Barnes (a general partner of OBP Management III L.P., the general partner of OBP Adjunct) may be deemed to beneficially own the shares held of record by OBP Adjunct. Mr. Barnes disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. Securities held of record by mRNA Fund L.P. ("mRNA"). Mr. Barnes (a general partner of mRNA Partners L.P., the general partner of mRNA) may be deemed to beneficially own the shares held of record by mRNA. Mr. Barnes disclaims beneficial ownership of such securities except to the extent of his pecuniary interest therein. /s/ Jeffrey T. Barnes 2005-12-14