X0202 4 2005-11-29 0000812121 CRITICARE SYSTEMS INC /DE/ CMD 0001095787 OXFORD BIOSCIENCE PARTNERS III LP 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340035 Oxford Bioscience Partners (Bermuda) III Limtied Partnership 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340039 Oxford Bioscience Partners (Adjunct) III L.P. 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340038 mRNA Fund L.P. 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340037 OBP Management III L.P. 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340036 OBP Management (Bermuda) III Limited Partnership 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001340034 mRNA Partners L.P. 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001261294 BARNES JEFFREY T 222 BERKELEY ST. BOSTON MA 02116 1 0 1 0 0001262294 FLEMING JONATHAN 222 BERKELEY ST. BOSTON MA 02116 0 0 1 0 0001214273 WALTON ALAN G 315 POST ROAD WEST WESTPORT CT 06880 0 0 1 0 Common Stock 2005-11-29 4 S 0 9612 4.80 D 1402802 D Common Stock 2005-11-29 4 S 0 1368 4.80 D 199935 I Oxford Bioscience Partners (Bermuda) III L.P. Common Stock 2005-11-29 4 S 0 900 4.80 D 131300 I Oxford Bioscience Partners (Adjunct) III L.P. Common Stock 2005-11-29 4 S 0 120 4.80 D 16636 I mRNA Fund L.P. Common Stock 2005-11-30 4 S 0 480 4.80 D 1402322 D Common Stock 2005-11-30 4 S 0 68 4.80 D 199867 I Oxford Bioscience Partners (Bermuda) III L.P. Comon Stock 2005-11-30 4 S 0 44 4.80 D 131256 I Oxford Bioscience Partners (Adjunct) III L.P. Common Stock 2005-11-30 4 S 0 8 4.80 D 16628 I mRNA Fund L.P. Securities held of record by Oxford Bioscience Partners III L.P. ("OBP"). By virtue of their relationship as affiliated limited partnerships whose general partners share general partners, Oxford Bioscience Partners (Adjunct) III L.P. ("OBP Adjunct"), Oxford Bioscience Partners (Bermuda) III Limited Partnership ("OBP Bermuda") and mRNA Fund L.P. ("mRNA") may be deemed to beneficially own the shares held of record by OBP. OBP Management III L.P. (the general partner of OBP and OBP Adjunct), OBP Management (Bermuda) III Limited Partnership (the general partner of OBP Bermuda) and mRNA Partners L.P. (the general partner of mRNA) may be deemed to beneficially own the shares held of record by OBP. Messrs. Barnes, Fleming, and Walton (the general partners of OBP Management III L.P.) may be deemed to beneficially own the shares held of record by OBP. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein. Securities held of record by OBP Bermuda. By virtue of their relationship as affiliated limited partnerships whose general partners share general partners, OBP, OBP Adjunct and mRNA may be deemed to benefically own the shares held of record by OBP Bermuda. OBP Management III L.P. (the general partner of of OBP and OBP Adjunct), OBP Management (Bermuda) III Limited Partnership (the general partner of OBP Bermuda) and mRNA Partners L.P. (the general partner of mRNA) may be deemed to benefically own the shares held of record by OBP Bermuda. Messrs. Barnes, Fleming, and Walton (the general partners of OBP Management (Bermuda) III Limited Partnership) may be deemed to beneficially own the shares held of record by OBP Bermuda. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein. Securities held of record by OBP Adjunct. By virtue of their relationship as affiliated limited partnerships whose general partners share general partners, OBP, OBP Bermuda and mRNA may be deemed to benefically own the shares held of record by OBP Adjunct. OBP Management III L.P. (the general partner of of OBP and OBP Adjunct), OBP Management (Bermuda) III Limited Partnership (the general partner of OBP Bermuda) and mRNA Partners L.P. (the general partner of mRNA) may be deemed to benefically own the shares held of record by OBP Adjunct. Messrs. Barnes, Fleming, and Walton (the general partners of OBP Management III L.P.) may be deemed to beneficially own the shares held of record by OBP Adjunct. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein. Securities held of record by mRNA. By virtue of their relationship as affiliated limited partnerships whose general partners share general partners, OBP, OBP Bermuda and OBP Adjunct may be deemed to benefically own the shares held of record by mRNA. OBP Management III L.P. (the general partner of of OBP and OBP Adjunct), OBP Management (Bermuda) III Limited Partnership (the general partner of OBP Bermuda) and mRNA Partners L.P. (the general partner of mRNA) may be deemed to benefically own the shares held of record by mRNA. Messrs. Barnes, Fleming, and Walton (the general partners of mRNA Partners L.P.) may be deemed to beneficially own the shares held of record by mRNA. The reporting persons disclaim beneficial ownership of such securities except to the extent of their pecuniary interest therein. /s/ Jeffrey T. Barnes, as general partner of the general partner of Oxford Bioscience Partners III L.P. 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of the general partner of Oxford Bioscience Partners (Bermuda) III Limited Partnership 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of the general partner of Oxford Bioscience Partners (Adjunct) III L.P. 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of the general partner of mRNA Fund L.P. 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of OBP Management III L.P. 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of OBP Management (Bermuda) III Limited Partnership 2005-12-02 /s/ Jeffrey T. Barnes, as general partner of mRNA Partners L.P. 2005-12-02 /s/ Jeffrey T. Barnes 2005-12-02 /s/ Raymond Charest, as attorney-in-fact for Jonathan J. Fleming 2005-12-02 /s/ Raymond Charest, as attorney-in-fact for Alan G. Walton 2005-12-02