Consolidated Statements of Stockholders' Equity (Unaudited) - USD ($)	Common Stock [Member]	Additional Paid-in Capital [Member]	Retained Earnings [Member]	AOCI Attributable to Parent [Member]		Noncontrolling Interest [Member]	Total
Balance (in shares) at Dec. 31, 2017	1,090,664
Balance at Dec. 31, 2017	$ 1,000	$ 221,381,000	$ (187,640,000)	$ (43,000)	[1]	$ (487,000)	$ 33,212,000
Stock-based compensation expense (in shares)	41
Stock-based compensation expense		652,000					652,000
Issuance of common stock and pre-funded warrants in financing, net of offering costs (in shares)	808,465
Issuance of common stock and pre-funded warrants in financing, net of offering costs	$ 1,000	6,628,000					6,629,000
Exercise of warrants (in shares)	269,167
Exercise of warrants		27,000					27,000
Discount due to beneficial conversion features		7,200,000			[1]		7,200,000
Cumulative-effect adjustment from adoption of ASC 606			(79,000)				(79,000)
Foreign currency translation				30,000	[1]		30,000
Net loss			(39,716,000)		[1]	(1,224,000)	(40,940,000)
Balance (in shares) at Dec. 31, 2018	2,168,337
Balance at Dec. 31, 2018	$ 2,000	235,888,000	(227,435,000)	(13,000)	[1]	(1,711,000)	6,731,000
Stock-based compensation expense		614,000			[1]		614,000
Issuance of common stock and pre-funded warrants in financing, net of offering costs (in shares)
Issuance of common stock and pre-funded warrants in financing, net of offering costs		756,000					756,000
Exercise of warrants (in shares)	18,764
Exercise of warrants		112,000					112,000
Discount due to beneficial conversion features		2,313,000			[1]		2,313,000
Foreign currency translation				15,000	[1]		15,000
Net loss			(9,497,000)		[1]	(602,000)	(10,099,000)
Exercise of pre-funded warrants (in shares)	416,500
Exercise of pre-funded warrants	$ 1,000	41,000			[1]		42,000
Conversion of note payable to stock (in shares)	240,000
Conversion of note payable to stock		432,000			[1]		432,000
Reorganization of subsidiary and related change in non-controlling interest		(2,843,000)			[1]	2,843,000
Balance (in shares) at Dec. 31, 2019	2,843,601
Balance at Dec. 31, 2019	$ 3,000	$ 237,313,000	$ (236,932,000)	$ 2,000	[1]	$ 530,000	$ 916,000

[1] Accumulated other comprehensive loss.