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Note 1 - Description of Business and Basis of Presentation (Details Textual) - USD ($)
3 Months Ended
Mar. 31, 2019
Jan. 01, 2019
Dec. 31, 2018
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance $ 956,000   $ (1,711,000)
Reorganization of Subsidiary and Related Change in Non-controlling Interest    
Cash and Cash Equivalents, at Carrying Value, Ending Balance 2,237,000   2,400,000
Working Capital 3,246,000    
Retained Earnings (Accumulated Deficit), Ending Balance (229,306,000)   $ (227,435,000)
Boyalife Investment Fund II, Inc. [Member] | Revolving Credit Facility [Member]      
Long-term Line of Credit, Total 8,713,000    
Line of Credit Facility, Maximum Borrowing Capacity 10,000,000    
Noncontrolling Interest [Member]      
Reorganization of Subsidiary and Related Change in Non-controlling Interest 2,843,000    
ThermoGenesis [Member]      
Ownership in Subsidiary Exchanged   20.00%  
Noncontrolling Interest, Ownership Percentage by Parent   100.00%  
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance (1,711,000)    
CAR-TXpress [Member]      
Minority Interest Acquired Through Exchange   20.00%  
Noncontrolling Interest, Ownership Percentage by Parent   80.00%  
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance $ 1,100,000