<SEC-DOCUMENT>0001437749-20-012350-index.html : 20200603
<SEC-HEADER>0001437749-20-012350.hdr.sgml : 20200603
<ACCEPTANCE-DATETIME>20200603164348
ACCESSION NUMBER:		0001437749-20-012350
CONFORMED SUBMISSION TYPE:	S-1
PUBLIC DOCUMENT COUNT:		7
FILED AS OF DATE:		20200603
DATE AS OF CHANGE:		20200603

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			NAVIDEA BIOPHARMACEUTICALS, INC.
		CENTRAL INDEX KEY:			0000810509
		STANDARD INDUSTRIAL CLASSIFICATION:	IN VITRO & IN VIVO DIAGNOSTIC SUBSTANCES [2835]
		IRS NUMBER:				311080091
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	FILING VALUES:
		FORM TYPE:		S-1
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	333-238911
		FILM NUMBER:		20940559

	BUSINESS ADDRESS:	
		STREET 1:		4995 BRADENTON AVENUE
		STREET 2:		SUITE 240
		CITY:			DUBLIN
		STATE:			OH
		ZIP:			43017
		BUSINESS PHONE:		6147937500

	MAIL ADDRESS:	
		STREET 1:		4995 BRADENTON AVENUE
		STREET 2:		SUITE 240
		CITY:			DUBLIN
		STATE:			OH
		ZIP:			43017

	FORMER COMPANY:	
		FORMER CONFORMED NAME:	NEOPROBE CORP
		DATE OF NAME CHANGE:	19940714
</SEC-HEADER>
<DOCUMENT>
<TYPE>S-1
<SEQUENCE>1
<FILENAME>navb20200602_s1.htm
<DESCRIPTION>FORM S-1
<TEXT>
Document 1 - file: navb20200602_s1.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-5.1
<SEQUENCE>2
<FILENAME>ex_189014.htm
<DESCRIPTION>EXHIBIT 5.1
<TEXT>
Document 2 - file: ex_189014.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>EX-23.1
<SEQUENCE>3
<FILENAME>ex_188987.htm
<DESCRIPTION>EXHIBIT 23.1
<TEXT>
Document 3 - file: ex_188987.htm

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>4
<FILENAME>altlogo5_1.jpg
<TEXT>
Document 4 - file: altlogo5_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>5
<FILENAME>footer5_1.jpg
<TEXT>
Document 5 - file: footer5_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>6
<FILENAME>logo5_1.jpg
<TEXT>
Document 6 - file: logo5_1.jpg

</DOCUMENT>
<DOCUMENT>
<TYPE>GRAPHIC
<SEQUENCE>7
<FILENAME>navlogo01.jpg
<TEXT>
Document 7 - file: navlogo01.jpg

</DOCUMENT>
</SEC-DOCUMENT>