Exhibit 21.1

Subsidiaries of Navidea Biopharmaceuticals, Inc.

Subsidiaries	Jurisdiction of Incorporation		Percentage Owned by Registrant
Cardiosonix Ltd.		Israel		100	%
Cira Biosciences, Inc.		Delaware, USA		90	%
RIGSTech I Corporation		Delaware, USA		100	%
Navidea Biopharmaceuticals Limited		United Kingdom		100	%