John Hancock Financial Services

U.S. Wealth Management

601 Congress Street

Boston, MA 02210

(617) 663-4324

Fax: (617) 663-2197

E-Mail: aouellette@jhancock.com

Name:   Alfred P. Ouellette

Title: Assistant Vice President and

Senior Counsel

March 4, 2008

EDGAR

U.S. Securities and Exchange Commission

100 F Street, N. E.

Washington, D.C. 20549

Re: John Hancock World Fund (the “Trust”) on behalf of

John Hancock Health Sciences Fund (the “Fund”)

File Nos. 811-4932 and 33-10722

CERTIFICATE UNDER RULE 497(j)

Gentlemen:

Pursuant to 497(j) of Regulation C, under the Securities Act of 1933, in lieu of filing under paragraph (b) or (c) of Rule 497, I hereby certify that the forms of the Classes A, B and C shares Prospectus and the Statement of Additional Information of the Fund dated March 1, 2008 for the above-captioned registrant, that would have been filed under paragraph (b) or (c) of Rule 497(j), do not differ from those contained in the most recent registration statement amendment and the text of the most recent registration statement has been filed electronically.

Sincerely,

/s/Alfred P. Ouellette

Alfred P. Ouellette

Assistant Secretary