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Derivative Instruments - Summary of Assumptions Used in Computing Fair Value (Detail) - $ / shares
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Convertible Notes [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 1.25 $ 1.25
Expected volatility rate 143.00% 140.00%
Remaining term of expected volatility 6 years 3 months 7 years 3 months
Risk-free interest rate 1.95% 1.97%
Expected dividend yield 0.00% 0.00%
Reimbursement Notes [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 0.50 $ 0.50
Expected volatility rate 143.00% 140.00%
Remaining term of expected volatility 6 years 3 months 7 years 3 months
Risk-free interest rate 1.95% 1.97%
Expected dividend yield 0.00% 0.00%
Bridge Notes [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 0.50 $ 0.50
Expected volatility rate 143.00% 140.00%
Remaining term of expected volatility 6 years 3 months 7 years 3 months
Risk-free interest rate 1.95% 1.97%
Expected dividend yield 0.00% 0.00%
Amended and Restated June 2010 Warrants [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 0.50 $ 0.50
Expected volatility rate 136.00% 160.00%
Remaining term of expected volatility 3 years 6 months 7 days 4 years 6 months 7 days
Risk-free interest rate 1.42% 1.51%
Expected dividend yield 0.00% 0.00%
Warrants [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 0.50 $ 0.50
Expected volatility rate 141.00% 161.00%
Remaining term of expected volatility 3 years 6 months 7 days 4 years 6 months 7 days
Risk-free interest rate 1.31% 1.65%
Expected dividend yield 0.00% 0.00%
August 2010 Investor Warrants [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price   $ 0.28
Fair value assumption conversion price   $ 1.26
Expected volatility rate   116.00%
Remaining term of expected volatility   7 months 24 days
Risk-free interest rate   0.12%
Expected dividend yield   0.00%
July 2011 Investor Warrants [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 1.09 $ 1.09
Expected volatility rate 88.00% 122.00%
Remaining term of expected volatility 6 months 4 days 1 year 6 months 4 days
Risk-free interest rate 0.49% 0.67%
Expected dividend yield 0.00% 0.00%
2013 Restructuring Warrants [Member]    
Fair Value Measurements, Recurring and Nonrecurring, Valuation Techniques [Line Items]    
Fair value assumption stock price $ 0.68 $ 0.28
Fair value assumption conversion price $ 0.50 $ 0.50
Expected volatility rate 141.00% 161.00%
Remaining term of expected volatility 3 years 6 months 7 days 4 years 6 months 7 days
Risk-free interest rate 1.31% 1.65%
Expected dividend yield 0.00% 0.00%