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Net income (loss) per share
6 Months Ended 12 Months Ended
Jun. 30, 2011
Dec. 31, 2010
Net income (loss) per share [Abstract]    
Net income (loss) per share
12. Net income (loss) per share
The following table sets forth the information needed to compute basic earnings per share:
                                 
    Three Months Ended   Six Months Ended
    June 30,   June 30,
    2011   2010 Restated   2011   2010 Restated
    (in thousands except per share data)   (in thousands except per share data)
Basic net income (loss)
  $ 1,842     $ (31,573 )   $ 12,841     $ (48,832 )
     
Effect of Dilutive Securities — MHR convertible note payable assumed conversion
    -0-       -0-       923       -0-  
     
Numerator for Diluted net income (loss) per share after assumed note conversion
    1,842       (31,573 )     13,764       (48,832 )
     
Weighted average common shares outstanding:
    52,076,602       43,338,432       52,064,171       42,711,367  
Dilutive securities
                               
Options
    221,124             309,457        
Warrants
    2,626,629             3,476,116        
     
Shares underlying MHR convertible note payable
                7,051,183        
     
Diluted weighted average common shares outstanding and assumed conversion
    54,924,355       43,338,432       62,900,927       42,711,367  
     
Basic net income (loss) per share
  $ 0.04     $ (0.73 )   $ 0.25     $ (1.14 )
Diluted net income (loss) per share
  $ 0.03     $ (0.73 )   $ 0.22     $ (1.14 )
For the three and six months periods ended June 30, 2011 and 2010, certain potential shares of common stock have been excluded from the calculation of diluted income (loss) per share because the exercise price was greater than the average market price of our common stock, and therefore, the effect on diluted loss per share would have been anti-dilutive. In addition incremental shares from the assumed conversion of the MRH note payable are excluded for the three month periods ended June 30, 2011 and 2010 and for the six month period ended June 30, 2010 as the effect of these shares is anti-dilutive in these periods. The following table sets forth the number of potential shares of common stock that have been excluded from diluted net income (loss) per share because their effect was anti-dilutive:
                                 
    Three Months Ended   Six Months Ended
    June 30,   June 30,
    2011   2010   2011   2010
Options to purchase common shares
    2,759,476       3,187,116       2,671,143       3,187,116  
Outstanding warrants
    9,018,697       6,954,391       8,169,210       6,954,391  
MHR convertible note payable
    7,051,181       6.319.856       -0-       6,319,856  
     
 
    18,829,354       16,461,363       10,840,353       16,461,363  
15. Net Loss Per Share
     The following table sets forth the information needed to compute basic and diluted earnings per share for the years ended December 31, 2010, 2009 and 2008:
                         
    Year Ended December 31,  
    2010     2009 restated     2008  
    (In thousands, except per share amounts)  
Basic and diluted net loss
  $ (56,909 )   $ (16,821 )   $ (24,388 )
 
                 
Weighted average common shares outstanding, basic and diluted
    46,206,803       34,679,321       30,337,442  
 
                 
Basic and diluted net loss per share
  $ (1.23 )   $ (0.49 )   $ (0.80 )
 
                 
     The following table sets forth the number of potential shares of common stock that have been excluded from diluted net loss per share because their effect was anti-dilutive:
                         
    Year Ended December 31,  
    2010     2009     2008  
Options to purchase common shares
    2,477,037       2,865,736       2,208,854  
Outstanding warrants and options to purchase warrants
    11,832,826       9,934,253       2,972,049  
Novartis convertible note payable
          14,944,980       7,537,921  
MHR note payable
    6,675,512       5,983,146       5,362,596  
 
                 
 
    20,985,375       33,728,115       18,081,420